| Course Objectives: |
The aim of this course is to provide a thorough understanding of the basic physical principles which underlie therapeutic uses of lasers in medicine. Laser-tissue interaction mechanisms will be examined.
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| Course Content: |
Wave motion, electromagnetic theory, electromagnetic spectrum, propagation of light , measurement of optical properties of tissues, optics, microscopy, lasers, mechanisms of laser-tissue ineractions, lasers in surgery, tissue welding, laser tweezers, lasers in imaging, diagnostic applications, electrosurgery versus laser surgery, laser safety.
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| Week |
Subject |
Related Preparation |
| 1) |
Introduction, wave motion; plane, spherical and cylindrical waves, Electromagnetic theory, electromagnetic waves, energy and momentum of radiation. Dipole emission, emission and absorption by atoms and molecules, black body radiation, electromagnetic spectrum.
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| 2) |
Propagation of light: reflection, refraction, scattering, interference and diffraction. Measurement of optical properties of tissue, Geometrical optics, fiberoptics. Microscopy and limits of resolution, mechanisms of contrast.
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| 3) |
Eye and vision, perception of color. Spontaneous and stimulated emission, principle of laser, cavity modes, lasing media, pumping mechanisms, continuous and pulsed regimes.
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| 4) |
"Mechanisms of laser-tissue interactions I: Photochemical. Photodynamic therapy,
photostimulation, cytotoxicity of UV light."
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| 5) |
Mechanisms of laser-tissue interactions II: Photothermal. Heat generation, heat conduction and distribution. Thermal damage to tissue. Laser-Induced Interstitial Thermotherapy (LIIT).
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| 6) |
Mechanisms of laser-tissue interactions III: Photomechanical. Explosive evaporation, shock and acoustic waves, cavitation, jet formation.
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| 7) |
Mechanisms of laser-tissue interactions IV: Dielectric breakdown, plasma-mediated ablation.
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| 8) |
Lasers in Ophthalmology.
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| 9) |
Lasers in Dermatology.
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| 10) |
Lasers in General Surgery, Cardiovascular Surgery, Gynecology. Tissue welding. Low power lasers. Micromanipulation and cell surgery.
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| 11) |
Lasers in Imaging.
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| 12) |
Diagnostic applications: Autofluorescence, Raman spectroscopy, Scattering Light Spectroscopy, Doppler velocimetry.
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| 13) |
"Electrosurgery: Mechanisms of interaction and tissue damage. Pros and cons vs.
laser surgery."
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| 14) |
Laser safety: lasers classification.
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BAHÇEŞEHİR UNIVERSITY BİLGİ PAKETİ / DERS KATALOĞU
