DIGITAL GAME DESIGN
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Course Introduction and Application Information

Course Code	Course Name	Semester	Theoretical	Practical	Credit	ECTS
BME4005	Laser-Tissue Interactions	Spring	3	0	3	6

This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction:	English
Type of course:	Non-Departmental Elective
Course Level:	Bachelor’s Degree (First Cycle)
Mode of Delivery:	Face to face
Course Coordinator :	Assist. Prof. HAKAN SOLMAZ
Course Objectives:	The aim of this course is to provide a thorough understanding of the basic physical principles which underlie therapeutic uses of lasers in medicine. Laser-tissue interaction mechanisms will be examined.

Learning Outcomes

The students who have succeeded in this course;
On completion successful students will be able to understand the mechanisms describing the interaction of laser radiation with biological tissue, spectroscopic and diagnostic optical applications of lasers in medicine, selected applications of lasers and optical techniques which are presently important in medicine.

Course Content

Wave motion, electromagnetic theory, electromagnetic spectrum, propagation of light , measurement of optical properties of tissues, optics, microscopy, lasers, mechanisms of laser-tissue ineractions, lasers in surgery, tissue welding, laser tweezers, lasers in imaging, diagnostic applications, electrosurgery versus laser surgery, laser safety.

Weekly Detailed Course Contents

Week	Subject	Related Preparation
1)	Introduction, wave motion; plane, spherical and cylindrical waves, Electromagnetic theory, electromagnetic waves, energy and momentum of radiation. Dipole emission, emission and absorption by atoms and molecules, black body radiation, electromagnetic spectrum.
2)	Propagation of light: reflection, refraction, scattering, interference and diffraction. Measurement of optical properties of tissue, Geometrical optics, fiberoptics. Microscopy and limits of resolution, mechanisms of contrast.
3)	Eye and vision, perception of color. Spontaneous and stimulated emission, principle of laser, cavity modes, lasing media, pumping mechanisms, continuous and pulsed regimes.
4)	"Mechanisms of laser-tissue interactions I: Photochemical. Photodynamic therapy, photostimulation, cytotoxicity of UV light."
5)	Mechanisms of laser-tissue interactions II: Photothermal. Heat generation, heat conduction and distribution. Thermal damage to tissue. Laser-Induced Interstitial Thermotherapy (LIIT).
6)	Mechanisms of laser-tissue interactions III: Photomechanical. Explosive evaporation, shock and acoustic waves, cavitation, jet formation.
7)	Mechanisms of laser-tissue interactions IV: Dielectric breakdown, plasma-mediated ablation.
8)	Lasers in Ophthalmology.
9)	Lasers in Dermatology.
10)	Lasers in General Surgery, Cardiovascular Surgery, Gynecology. Tissue welding. Low power lasers. Micromanipulation and cell surgery.
11)	Lasers in Imaging.
12)	Diagnostic applications: Autofluorescence, Raman spectroscopy, Scattering Light Spectroscopy, Doppler velocimetry.
13)	"Electrosurgery: Mechanisms of interaction and tissue damage. Pros and cons vs. laser surgery."
14)	Laser safety: lasers classification.

Sources

Course Notes / Textbooks:	M. H. Niemz, Laser tissue interactions, Springer Verlag. ISBN 354-060-3638
References:	Lasers in Medical Science (SpringerLINK 1998-), Lasers in Surgery and Medicine (WILEY 1997-)

Evaluation System

Semester Requirements	Number of Activities	Level of Contribution
Presentation	1	% 40
Final	1	% 60
Total		% 100
PERCENTAGE OF SEMESTER WORK		% 40
PERCENTAGE OF FINAL WORK		% 60
Total		% 100

ECTS / Workload Table

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	3	42
Study Hours Out of Class	14	8	112
Midterms	2	2	4
Final	1	2	2
Total Workload			160

Contribution of Learning Outcomes to Programme Outcomes

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Comprehend the conceptual importance of the game in the field of communication, ability to implement the player centered application to provide design.
2)	Analyze, synthesize, and evaluate information and ideas from various perspectives.
3)	Analyze the key elements that make up specific game genres, forms of interactions, mode of narratives and understand how they are employed effectively to create a successful game.
4)	Understand game design theories and methods as well as implement them during game development; to make enjoyable, attractive, instructional and immersive according to the target audience.
5)	Understand the technology and computational principles involved in developing games and master the use of game engines.
6)	Understand the process of creation and use of 2D and 3D assets and animation for video games.
7)	Understand and master the theories and methodologies of understanding and measuring player experience and utilize them during game development process.
8)	Comprehend and master how ideas, concepts and topics are conveyed via games followed by the utilization of these aspects during the development process.
9)	Manage the game design and development process employing complete documentation; following the full game production pipeline via documentation.
10)	Understand and employ the structure and work modes of game development teams; comprehend the responsibilities of team members and collaborations between them while utilizing this knowledge in practice.
11)	Understand the process of game publishing within industry standards besides development and utilize this knowledge practice.
12)	Pitching a video game to developers, publishers, and players; mastering the art of effectively communicating and marketing the features and commercial potential of new ideas, concepts or games.