MOLECULAR BIOLOGY AND GENETICS
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Course Introduction and Application Information

Course Code	Course Name	Semester	Theoretical	Practical	Credit	ECTS
MBG2002	Molecular Genetics II	Spring	3	2	4	7

Basic information

Language of instruction:	English
Type of course:	Must Course
Course Level:	Bachelor’s Degree (First Cycle)
Mode of Delivery:	Face to face
Course Coordinator :	Dr. Öğr. Üyesi ELIZABETH HEMOND
Course Objectives:	The objective of the course is to identify chromosome structure, its impact on gene expression regulation, epigenetics, RNA procession and RNA editing.

Learning Outcomes

The students who have succeeded in this course;
1. Identifiy chromosome structure,
2. Discuss nucleosome structure,
3. Define gene regulatory sequences,
4. Identify activation of transcription,
5. Discuss epigenetic mechanisms,
6. Define inheritance of genetics,
7. Discuss RNA processing,
8. Identify catalytic RNAs,
9. Discuss RNA editing

Course Content

The course content includes molecular biology of eukaryotes with genome organization and chromosome structure, gene structure, protein structure and synthesis, regulation of gene expression, RNA splicing and processing, catalytic RNAs and RNA editing.

Weekly Detailed Course Contents

Week	Subject	Related Preparation
1)	Chromosomes
2)	Nucleosome structure I
3)	Nucleosome structure II
4)	Gene regulatory sequences (Promoters and Enhancers) I
5)	Gene regulatory sequences (Promoters and Enhancers) II
6)	Activation of Transcription I
7)	Activation of Transcription II
8)	Epigenetic Mechanisms I
9)	Epigenetic Mechanisms II
10)	Inheritance of epigenetics
11)	RNA processing
12)	Catalytic RNA I
13)	Catalytic RNA II
14)	RNA editing

Sources

Course Notes / Textbooks:	Moleküler Genetik II ders notları haftalık verilecektir. Molecular Genetics II Lecture Notes will be supplied weekly.
References:	1. The Cell: A Molecular Approach, Geoffrey M. Cooper, Robert E. Hausman, Sinauer Associates, 5th edition (2009), ISBN-13: 978-0878933976 2. Molecular Biology of the Gene. (4th ed.) 1987. James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine (Author), Richard Losick, Inglis CSHLP., Benjamin Cummings Publishers, 6th edition (2007), ISBN-13: 978-0805395921

Evaluation System

Semester Requirements	Number of Activities	Level of Contribution
Attendance	1	% 5
Laboratory	2	% 20
Midterms	1	% 25
Final	1	% 50
Total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
Total		% 100

ECTS / Workload Table

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	3	42
Laboratory	10	2	20
Study Hours Out of Class	14	8	112
Midterms	1	2	2
Final	1	2	2
Total Workload			178

Contribution of Learning Outcomes to Programme Outcomes

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Utilize the wealth of information stored in computer databases to answer basic biological questions and solve problems such as diagnosis and treatment of diseases.	5
2)	Acquire an ability to compile and analyze biological information, clearly present and discuss the conclusions, the inferred knowledge and the arguments behind them both in oral and written format.	5
3)	Develop critical, creative and analytical thinking skills.	5
4)	Develop effective communication skills and have competence in scientific speaking, reading and writing abilities in English and Turkish.	5
5)	Gain knowledge of different techniques and methods used in genetics and acquire the relevant laboratory skills.	2
6)	Detect biological problems, learn to make hypothesis and solve the hypothesis by using variety of experimental and observational methods.	5
7)	Gain knowledge of methods for collecting quantitative and qualitative data and obtain the related skills.	5
8)	Conduct research through paying attention to ethics, human values and rights. Pay special attention to confidentiality of information while working with human subjects.	5
9)	Obtain basic concepts used in theory and practices of molecular biology and genetics and establish associations between them.	5
10)	Search and use literature to improve himself/herself and follow recent developments in science and technology.	5
11)	Be aware of the national and international problems in the field and search for solutions.	3