MOLECULAR BIOLOGY AND GENETICS
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Course Introduction and Application Information

Course Code	Course Name	Semester	Theoretical	Practical	Credit	ECTS
MBG2001	Molecular Genetics I	Fall	3	2	4	7

Basic information

Language of instruction:	English
Type of course:	Must Course
Course Level:	Bachelor’s Degree (First Cycle)
Mode of Delivery:	Face to face
Course Coordinator :	Dr. Öğr. Üyesi ELIZABETH HEMOND
Course Objectives:	The objective of the course is to identify the features of nucleic acids, chromosome organization in prokaryotes and eukaryotes, DNA replication and the mechanisms related with gene expression.

Learning Outcomes

The students who have succeeded in this course;
1. Identify preliminary terms in genetics.
2. Discuss the basic features of DNA.
3. Define structure and features of nucleic acids.
4. Identify chromosome organization in prokaryotes and eukaryotes.
5. Discuss DNA replication.
6. Discuss mutations, their causes and types.
7. Define DNA repair and its mechanisms.
8. Discuss RNA transcription.
9. Identifies RNA processing in general terms.
10. Discuss mechanisms related with gene expression regulation
11. Identify protein translation.
12. Discuss post-translational mechanisms.

Course Content

This course covers the features of nucleic acids, chromosomeal organisation in prokaryotes and eukaryotes, DNA replication, RNA transcription and protein translation.

Weekly Detailed Course Contents

Week	Subject	Related Preparation
1)	Introduction
2)	DNA
3)	Structure and properties of nucleic acids
4)	Chromosome organization in prokaryotes and eukaryotes
5)	DNA Replication
6)	Mutations
7)	DNA repair
8)	Transcription I
9)	Transcription II
10)	RNA processing
11)	Regulation of gene expression
12)	Translation I
13)	Translation II
14)	Post-translational modifications

Sources

Course Notes / Textbooks:	Molecular Genetics I Lecture Notes will be supplied. Moleküler Genetik I ders notları verilecektir.
References:	1. The Cell: A Molecular Approach, Geoffrey M. Cooper, Robert E. Hausman, Sinauer Associates, 5th edition (2009), ISBN-13: 978-0878933976 2. Molecular Biology of the Gene. (4th ed.) 1987. James D. Watson, Tania A. Baker, Stephen P. Bell, Alexander Gann, Michael Levine (Author), Richard Losick, Inglis CSHLP., Benjamin Cummings Publishers, 6th edition (2007), ISBN-13: 978-0805395921

Evaluation System

Semester Requirements	Number of Activities	Level of Contribution
Attendance	10	% 5
Laboratory	10	% 20
Midterms	1	% 25
Final	1	% 50
Total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
Total		% 100

ECTS / Workload Table

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	3	42
Laboratory	10	2	20
Study Hours Out of Class	14	8	112
Midterms	1	2	2
Final	1	2	2
Total Workload			178

Contribution of Learning Outcomes to Programme Outcomes

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Utilize the wealth of information stored in computer databases to answer basic biological questions and solve problems such as diagnosis and treatment of diseases.	5
2)	Acquire an ability to compile and analyze biological information, clearly present and discuss the conclusions, the inferred knowledge and the arguments behind them both in oral and written format.	4
3)	Develop critical, creative and analytical thinking skills.	5
4)	Develop effective communication skills and have competence in scientific speaking, reading and writing abilities in English and Turkish.	5
5)	Gain knowledge of different techniques and methods used in genetics and acquire the relevant laboratory skills.	2
6)	Detect biological problems, learn to make hypothesis and solve the hypothesis by using variety of experimental and observational methods.	5
7)	Gain knowledge of methods for collecting quantitative and qualitative data and obtain the related skills.	5
8)	Conduct research through paying attention to ethics, human values and rights. Pay special attention to confidentiality of information while working with human subjects.	4
9)	Obtain basic concepts used in theory and practices of molecular biology and genetics and establish associations between them.	4
10)	Search and use literature to improve himself/herself and follow recent developments in science and technology.	5
11)	Be aware of the national and international problems in the field and search for solutions.	2