DIGITAL GAME DESIGN
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Course Introduction and Application Information

Course Code	Course Name	Semester	Theoretical	Practical	Credit	ECTS
MBG4066	Cancer Genetics and Biology	Spring	3	0	3	6

This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction:	English
Type of course:	Non-Departmental Elective
Course Level:	Bachelor’s Degree (First Cycle)
Mode of Delivery:	Face to face
Course Coordinator :	Assist. Prof. DİLEK ÇEVİK
Course Objectives:	The course will provide the student with a comprehensive insight into the molecular biology and genetics of cancer with an awareness of the complexity of cancer biology. Lectures will primarily focus on the role of growth factors, oncogenes, tumor suppressor and cell stress mechanisms such as apoptosis, senescence, and autophagy. The fundamental principles behind cancer diagnosis, prevention, and targeted molecular therapy will also be discussed. Recent articles regarding cancer will be studied and students will present a subject of interest regarding cancer.

Learning Outcomes

The students who have succeeded in this course;
1. Understand the molecular and cellular mechanisms leading to cancer.
2. Describe the genetic event causing oncogenesis.
3. Discuss hallmarks of cancer and cellular stress mechanisms.
4. Discuss cell cycle, apoptosis, and multicellular interactions in cancer.
5. Describe the fundamental principles behind molecular cancer diagnosis.
6. Have an overview of methodologies used in cancer research.
7. Read and discuss cancer related research articles.

Course Content

Genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Weekly Detailed Course Contents

Week	Subject	Related Preparation
1)	Cancer Epidemiology and Terminology	Reading the Chapter notes
2)	The Nature of Cancer	Reading the chapter notes
3)	Cancer as an Infectious Disease	Reading the chapter notes
4)	Oncogenes	Reading the chapter notes
5)	Tumor Suppressor Genes	Reading the chapter notes
6)	pRB and Control of Cell Cycle Clock	Reading the chapter notes
7)	p53 and Cancer	Reading the chapter notes
8)	DNA damage response in cancer cells	Reading the chapter notes
10)	DNA repair and cancer	Reading the chapter notes
11)	Senescence aberrations in cancer cells	Reading the chapter notes
12)	Apoptotic and autophagic aberrations in cancer cells	Reading the chapter notes
13)	Article Discussions and Student presentations	Reading the articles to be presented before class.
14)	Article Discussions and Student presentations	Reading the articles to be presented before class.

Sources

Course Notes / Textbooks:	Course Book: The Biology of Cancer, 3rd Edition by Robert Weinberg. Öğrencilere okuma materyali olarak bilimsel makaleler verilecektir.
References:	Course Book: The Biology of Cancer, 3rd Edition by Robert Weinberg. Scientific articles will also be assigned to students as reading material.

Evaluation System

Semester Requirements	Number of Activities	Level of Contribution
Homework Assignments	1	% 5
Presentation	1	% 10
Midterms	1	% 30
Final	1	% 50
Paper Submission	1	% 5
Total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
Total		% 100

ECTS / Workload Table

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	3	42
Study Hours Out of Class	14	4	56
Presentations / Seminar	1	10	10
Project	1	10	10
Homework Assignments	1	10	10
Midterms	1	3	3
Paper Submission	1	10	10
Final	1	3	3
Total Workload			144

Contribution of Learning Outcomes to Programme Outcomes

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Comprehend the conceptual importance of the game in the field of communication, ability to implement the player centered application to provide design.
2)	Analyze, synthesize, and evaluate information and ideas from various perspectives.
3)	Analyze the key elements that make up specific game genres, forms of interactions, mode of narratives and understand how they are employed effectively to create a successful game.
4)	Understand game design theories and methods as well as implement them during game development; to make enjoyable, attractive, instructional and immersive according to the target audience.
5)	Understand the technology and computational principles involved in developing games and master the use of game engines.
6)	Understand the process of creation and use of 2D and 3D assets and animation for video games.
7)	Understand and master the theories and methodologies of understanding and measuring player experience and utilize them during game development process.
8)	Comprehend and master how ideas, concepts and topics are conveyed via games followed by the utilization of these aspects during the development process.
9)	Manage the game design and development process employing complete documentation; following the full game production pipeline via documentation.
10)	Understand and employ the structure and work modes of game development teams; comprehend the responsibilities of team members and collaborations between them while utilizing this knowledge in practice.
11)	Understand the process of game publishing within industry standards besides development and utilize this knowledge practice.
12)	Pitching a video game to developers, publishers, and players; mastering the art of effectively communicating and marketing the features and commercial potential of new ideas, concepts or games.