MOLECULAR BIOLOGY AND GENETICS
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Course Introduction and Application Information

Course Code	Course Name	Semester	Theoretical	Practical	Credit	ECTS
MBG2003	Computation for Biological Sciences I	Fall	2	2	3	7

Basic information

Language of instruction:	English
Type of course:	Must Course
Course Level:	Bachelor’s Degree (First Cycle)
Mode of Delivery:	Face to face
Course Coordinator :	Dr. Öğr. Üyesi ELIZABETH HEMOND
Course Lecturer(s):	Dr. Öğr. Üyesi SERKAN AYVAZ Prof. Dr. SÜREYYA AKYÜZ
Course Objectives:	This class intended to provide a general introduction to computational tools for biology.

Learning Outcomes

The students who have succeeded in this course;
1. Have learned important biological data sources.
2. Can evaluate the results of biological analysis statistically and mathematically.
3. Have learned how to use various tools to evaluate genome sequencing data.
4. Have learned basic level analyses in Matlab.

Course Content

Evaluation and analysis of general biological and genome sequencing data using related computational tools efficiently.

Weekly Detailed Course Contents

Week	Subject	Related Preparation
1)	Biological data
2)	Biyological databases
3)	Sequencing data
4)	Sequence alignment
5)	Genome sequencing data
6)	Genome assembly
7)	Genetic variation analysis I
8)	Genetic variation analysis II
9)	Gene expression analysis
10)	Microarray data analysis
11)	Mass Spec analysis
12)	Molecular modelling I
13)	Molecular modelling II
14)	Molecular modelling III

Sources

Course Notes / Textbooks:	Ders notları verilecektir. Course notes will be supplied.
References:	Computational Biology Series Editors: Dress, A., Linial, M., Troyanskaya, O., Vingron, M. ISSN: 1568-2684, 2009

Evaluation System

Semester Requirements	Number of Activities	Level of Contribution
Attendance	10	% 10
Presentation	1	% 15
Midterms	1	% 25
Final	1	% 50
Total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
Total		% 100

ECTS / Workload Table

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	4	56
Study Hours Out of Class	14	7	98
Presentations / Seminar	5	4	20
Midterms	1	2	2
Final	1	2	2
Total Workload			178

Contribution of Learning Outcomes to Programme Outcomes

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Utilize the wealth of information stored in computer databases to answer basic biological questions and solve problems such as diagnosis and treatment of diseases.	4
2)	Acquire an ability to compile and analyze biological information, clearly present and discuss the conclusions, the inferred knowledge and the arguments behind them both in oral and written format.	5
3)	Develop critical, creative and analytical thinking skills.	5
4)	Develop effective communication skills and have competence in scientific speaking, reading and writing abilities in English and Turkish.	4
5)	Gain knowledge of different techniques and methods used in genetics and acquire the relevant laboratory skills.	3
6)	Detect biological problems, learn to make hypothesis and solve the hypothesis by using variety of experimental and observational methods.	5
7)	Gain knowledge of methods for collecting quantitative and qualitative data and obtain the related skills.	3
8)	Conduct research through paying attention to ethics, human values and rights. Pay special attention to confidentiality of information while working with human subjects.	5
9)	Obtain basic concepts used in theory and practices of molecular biology and genetics and establish associations between them.	4
10)	Search and use literature to improve himself/herself and follow recent developments in science and technology.	5
11)	Be aware of the national and international problems in the field and search for solutions.	4