INTERIOR ARCHITECTURE AND ENVIRONMENTAL DESIGN
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Course Introduction and Application Information

Course Code	Course Name	Semester	Theoretical	Practical	Credit	ECTS
MBG4066	Cancer Genetics and Biology	Spring Fall	3	0	3	6

This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction:	English
Type of course:	Non-Departmental Elective
Course Level:	Bachelor’s Degree (First Cycle)
Mode of Delivery:	Face to face
Course Coordinator :	Assist. Prof. DİLEK ÇEVİK
Course Objectives:	The course will provide the student with a comprehensive insight into the molecular biology and genetics of cancer with an awareness of the complexity of cancer biology. Lectures will primarily focus on the role of growth factors, oncogenes, tumor suppressor and cell stress mechanisms such as apoptosis, senescence, and autophagy. The fundamental principles behind cancer diagnosis, prevention, and targeted molecular therapy will also be discussed. Recent articles regarding cancer will be studied and students will present a subject of interest regarding cancer.

Learning Outcomes

The students who have succeeded in this course;
1. Understand the molecular and cellular mechanisms leading to cancer.
2. Describe the genetic event causing oncogenesis.
3. Discuss hallmarks of cancer and cellular stress mechanisms.
4. Discuss cell cycle, apoptosis, and multicellular interactions in cancer.
5. Describe the fundamental principles behind molecular cancer diagnosis.
6. Have an overview of methodologies used in cancer research.
7. Read and discuss cancer related research articles.

Course Content

Genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Weekly Detailed Course Contents

Week	Subject	Related Preparation
1)	Cancer Epidemiology and Terminology	Reading the Chapter notes
2)	The Nature of Cancer	Reading the chapter notes
3)	Cancer as an Infectious Disease	Reading the chapter notes
4)	Oncogenes	Reading the chapter notes
5)	Tumor Suppressor Genes	Reading the chapter notes
6)	pRB and Control of Cell Cycle Clock	Reading the chapter notes
7)	p53 and Cancer	Reading the chapter notes
8)	DNA damage response in cancer cells	Reading the chapter notes
10)	DNA repair and cancer	Reading the chapter notes
11)	Senescence aberrations in cancer cells	Reading the chapter notes
12)	Apoptotic and autophagic aberrations in cancer cells	Reading the chapter notes
13)	Article Discussions and Student presentations	Reading the articles to be presented before class.
14)	Article Discussions and Student presentations	Reading the articles to be presented before class.

Sources

Course Notes / Textbooks:	Course Book: The Biology of Cancer, 3rd Edition by Robert Weinberg. Öğrencilere okuma materyali olarak bilimsel makaleler verilecektir.
References:	Course Book: The Biology of Cancer, 3rd Edition by Robert Weinberg. Scientific articles will also be assigned to students as reading material.

Evaluation System

Semester Requirements	Number of Activities	Level of Contribution
Homework Assignments	1	% 5
Presentation	1	% 10
Midterms	1	% 30
Final	1	% 50
Paper Submission	1	% 5
Total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
Total		% 100

ECTS / Workload Table

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	3	42
Study Hours Out of Class	14	4	56
Presentations / Seminar	1	10	10
Project	1	10	10
Homework Assignments	1	10	10
Midterms	1	3	3
Paper Submission	1	10	10
Final	1	3	3
Total Workload			144

Contribution of Learning Outcomes to Programme Outcomes

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Engages in design, planning, and implementation activities in the field of interior architecture that can respond to different spatial configurations, user groups, and needs in national and international contexts,
2)	Analyzes data collected by focusing on user needs alongside real physical, social, and economic constraints, synthesizes various information and thoughts using individual and professional skills of the 21st century, and uses these processes to develop creative spatial solutions.
3)	Produces creative, innovative, aesthetic, and original spatial solutions using abstract and concrete concepts,
4)	Uses contemporary knowledge production, expression, representation, and technologies required by the field of interior architecture,
5)	Gains knowledge about contemporary spatial fittings and construction techniques in design and implementation works in the field of interior architecture; follows the industry and current developments,
6)	Embraces and prioritizes the relationship between human-environment, user health and safety, universal design principles, and sustainable design approaches in the field of interior architecture,
7)	Acquires a design understanding that respects the social and cultural rights of society, cultural heritage, and nature, and can make conscious decisions on these matters.
8)	Follows national and international values and developments in the fields of interior architecture, architecture, design, and art, participates in teamworks, interdisciplinary and multidisciplinary work, and is knowledgeable in ethical issues,
9)	Gains an understanding of legal regulations and standards in interior architecture; and becomes aware of professional ethics and responsibilities.