NEW MEDIA
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Course Introduction and Application Information

Course Code	Course Name	Semester	Theoretical	Practical	Credit	ECTS
MBG4066	Cancer Genetics and Biology	Fall	3	0	3	6

This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction:	English
Type of course:	Non-Departmental Elective
Course Level:	Bachelor’s Degree (First Cycle)
Mode of Delivery:	Face to face
Course Coordinator :	Dr. Öğr. Üyesi ELIZABETH HEMOND
Course Objectives:	In this course, student should learn about genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Learning Outcomes

The students who have succeeded in this course;
1. Have a general knowledge on genetic changes induced by cancer.
2. Discuss terms of oncogene and tumor suppressor gene.
3. Understand hereditary cancers and DNA repair cancer relationship.
4. Discuss cell cycle, apoptosis and multicellular cell interactions in cancer.

Course Content

Genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Weekly Detailed Course Contents

Week	Subject	Related Preparation
1)	Cancer as a disease
2)	Model organisms and techniques used in cancer studies
3)	Mutated genomes of cancer cells, DNA gains, DNA losses and nucleotide changes
4)	Epigenetic changes in cancer cells
5)	Viral and cellular oncogenes
6)	Tumor suppressor genes
7)	Overview of phenotypic changes in cancer cells
8)	Cell cycle and cancer
9)	DNA damage response in cancer cells
10)	DNA repair and cancer
11)	Senescence aberrations in cancer cells
12)	Apoptotic and autophagic aberrations in cancer cells
13)	Invasive and metastatic abilities of cancer cells
14)	Tumor heterogeneity and "cancer stem cells"

Sources

Course Notes / Textbooks:	The Molecular Basis of Cancer.2nd edition Author(s): Mendelsohn, Howley, Israel & Liotta. Publisher: W. B. Saunders Company, Philadelphia, 2011
References:	The Genetic Basis of Human Cancer Author(s): B. Vogelstein & K. W. Kinzler Publisher: McGraw-Hill, New York, 1999

Evaluation System

Semester Requirements	Number of Activities	Level of Contribution
Attendance	10	% 5
Homework Assignments	1	% 15
Midterms	1	% 30
Final	1	% 50
Total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
Total		% 100

ECTS / Workload Table

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	3	42
Study Hours Out of Class	14	8	112
Midterms	1	2	2
Final	1	2	2
Total Workload			158

Contribution of Learning Outcomes to Programme Outcomes

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	To be able to critically interpret and discuss the theories, the concepts, the traditions, and the developments in the history of thought which are fundamental for the field of new media, journalism and communication.
2)	To be able to attain written, oral and visual knowledge about technical equipment and software used in the process of news and the content production in new media, and to be able to acquire effective abilities to use them on a professional level.
3)	To be able to get information about the institutional agents and generally about the sector operating in the field of new media, journalism and communication, and to be able to critically evaluate them.
4)	To be able to comprehend the reactions of the readers, the listeners, the audiences and the users to the changing roles of media environments, and to be able to provide and circulate an original contents for them and to predict future trends.
5)	To be able to apprehend the basic theories, the concepts and the thoughts related to neighbouring fields of new media and journalism in a critical manner.
6)	To be able to grasp global and technological changes in the field of communication, and the relations due to with their effects on the local agents.
7)	To be able to develop skills on gathering necessary data by using scientific methods, analyzing and circulating them in order to produce content.
8)	To be able to develop acquired knowledge, skills and competence upon social aims by being legally and ethically responsible for a lifetime, and to be able to use them in order to provide social benefit.
9)	To be able to operate collaborative projects with national/international colleagues in the field of new media, journalism and communication.
10)	To be able to improve skills on creating works in various formats and which are qualified to be published on the prestigious national and international channels.