BAHÇEŞEHİR UNIVERSITY BİLGİ PAKETİ / DERS KATALOĞU
| MOLECULAR BIOLOGY AND GENETICS | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
Course Introduction and Application Information
| Course Code | Course Name | Semester | Theoretical | Practical | Credit | ECTS |
| MBG4065 | Introduction to Stem Cells | Spring | 3 | 0 | 3 | 6 |
| This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester. |
Basic information
| Language of instruction: | English |
| Type of course: | Departmental Elective |
| Course Level: | Bachelor’s Degree (First Cycle) |
| Mode of Delivery: | Face to face |
| Course Coordinator : | Dr. Öğr. Üyesi ELIZABETH HEMOND |
| Course Objectives: | In this course, student should learn about the basic biology of embryonic, adult and cancer stem cells, molecular mechanisms of self renewal, differentiation and plasticity, reproductive and therapeutic cloning, epigenetic changes associated with stem cells, use of stem cells in cell based therapies and its ethical considerations. |
Learning Outcomes
|
The students who have succeeded in this course; 1. Have a general understanding on stem cell biology. 2. Learn the basic features of stem cells and discuss the related mechanisms beneath. 3. Understand the effects of stem cells on the epigenetic changes. 4. Discuss stem cell based therapies and the related ethical issues stem from the uses of those therapies. 5. Categorize the stem cells. |
Course Content
| Basic biology of embryonic, adult and cancer stem cells. Molecular mechanisms of self renewal, differentiation and plasticity. Reproductive and therapeutic cloning. Epigenetic changes associated with stem cells. Use of stem cells in cell based therapies and its ethical considerations. |
Weekly Detailed Course Contents
| Week | Subject | Related Preparation |
| 1) | Introduction and classification of stem cells | |
| 2) | Basic biology of stem cells (self-renewal, pluripotency, plasticity, asymmetric division, niche) | |
| 3) | Embryonic Stem Cells | |
| 4) | Epiblast Stem Cells | |
| 5) | Induced Pluripotent Stem Cells | |
| 6) | Germline Stem Cells, Epigenetic Reprogramming I | |
| 7) | Germline Stem Cells, Epigenetic Reprogramming II | |
| 8) | Cancer Stem Cells | |
| 9) | Mesenchymal Stem Cells | |
| 10) | Hematopoeitic stem cells | |
| 11) | Organ Specific Stem Cells (Neural- Vascular Endothelial, Pancreatic) | |
| 12) | Organ Specific Stem Cells (Hepatic, Cardiac) | |
| 13) | Organ Specific Stem Cells (Epidermal, Lung) | |
| 14) | Review |
Sources
| Course Notes / Textbooks: | Weekly course notes will be provided |
| References: | Stem Cells Handbook, Steward Sell Publisher, 2003,ISBN 13: 9781588291134 |
Evaluation System
| Semester Requirements | Number of Activities | Level of Contribution |
| Attendance | 10 | % 5 |
| Homework Assignments | 1 | % 15 |
| Midterms | 1 | % 30 |
| Final | 1 | % 50 |
| Total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 50 | |
| PERCENTAGE OF FINAL WORK | % 50 | |
| Total | % 100 | |
ECTS / Workload Table
| Activities | Number of Activities | Duration (Hours) | Workload |
| Course Hours | 14 | 3 | 42 |
| Study Hours Out of Class | 14 | 8 | 112 |
| Midterms | 1 | 2 | 2 |
| Final | 1 | 2 | 2 |
| Total Workload | 158 | ||
Contribution of Learning Outcomes to Programme Outcomes
| No Effect | 1 Lowest | 2 Low | 3 Average | 4 High | 5 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Utilize the wealth of information stored in computer databases to answer basic biological questions and solve problems such as diagnosis and treatment of diseases. | 5 |
| 2) | Acquire an ability to compile and analyze biological information, clearly present and discuss the conclusions, the inferred knowledge and the arguments behind them both in oral and written format. | 4 |
| 3) | Develop critical, creative and analytical thinking skills. | 5 |
| 4) | Develop effective communication skills and have competence in scientific speaking, reading and writing abilities in English and Turkish. | 5 |
| 5) | Gain knowledge of different techniques and methods used in genetics and acquire the relevant laboratory skills. | 2 |
| 6) | Detect biological problems, learn to make hypothesis and solve the hypothesis by using variety of experimental and observational methods. | 5 |
| 7) | Gain knowledge of methods for collecting quantitative and qualitative data and obtain the related skills. | 4 |
| 8) | Conduct research through paying attention to ethics, human values and rights. Pay special attention to confidentiality of information while working with human subjects. | 5 |
| 9) | Obtain basic concepts used in theory and practices of molecular biology and genetics and establish associations between them. | 3 |
| 10) | Search and use literature to improve himself/herself and follow recent developments in science and technology. | 4 |
| 11) | Be aware of the national and international problems in the field and search for solutions. | 3 |