BNG5115 Cell and Tissue EngineeringBahçeşehir UniversityDegree Programs MOLECULAR BIOLOGY AND GENETICSGeneral Information For StudentsDiploma SupplementErasmus Policy StatementNational QualificationsBologna Commission
MOLECULAR BIOLOGY AND GENETICS
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
BNG5115 Cell and Tissue Engineering Spring 3 0 3 12
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction: English
Type of course: Departmental Elective
Course Level: Bachelor’s Degree (First Cycle)
Mode of Delivery: Face to face
Course Coordinator : Prof. Dr. GÜLAY BULUT
Recommended Optional Program Components: There is none.
Course Objectives: Tissue Engineering is an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function or a whole. This introductory course aims to address the most important and fundamental topics - biological as well as engineering - of contemporary tissue engineering research.

Learning Outcomes

The students who have succeeded in this course;
1. Provide students with a foundation for engineering tissues based on Nature's own design and optimization criteria.
2. Stimulate the students' ability to critically review recent published work in the field
3. Provide students with the necessary background and vocabulary to communicate with biomedical experts and clinicians.

Course Content

Tissue Engineering is an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function or a whole. This introductory course aims to address the most important and fundamental topics - biological as well as engineering - of contemporary tissue engineering research.

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Tissue Engineering
2) Surface immobilization of adhesion ligands for investigations of cell-substrate interactions
3) Biomaterials: Protein-surface interactions
4) Engineering biomaterials for tissue engineering: The 10–100 micron size scale
5) Regeneration templates
6) Fluid shear stress effects on cellular function
7) The biology of stem cells
8) Cell motility and tissue architecture
9) Midterm
10) The importance of stromal cells
11) Tissue engineering of bone and skeletal muscle
12) Tissue engineering of the liver & cartilage
13) Tissue engineering in the nervous system
14) Final

Sources

Course Notes / Textbooks: 1. Animal Cell Culture: Essential Methods, Wiley, John M. Davis, 2011, ISBN10: 9780470666586
2. Tissue Engineering, CRC Press, Bernhard Palsson, Jeffrey A. Hubbell, Robert Plonsey, Joseph D. Bronzino, 2003, ISBN10: 9780849318122
3. Stem Cell Engineering: Principles and Practices, CRC Press, David Schaffer, Joseph D. Bronzino, Donald R. Peterson, 2012, ISBN10: 9781439872048
4. Tissue Engineering: Principles and Practices, CRC Press, John P. Fisher, Antonios G. Mikos, Joseph D.Bronzino, Donald R. Peterson, 2012, ISBN10: 9781439874004
References: Lecture notes.

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Attendance 1 % 10
Midterms 1 % 30
Final 1 % 60
Total % 100
PERCENTAGE OF SEMESTER WORK % 40
PERCENTAGE OF FINAL WORK % 60
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 4 56
Study Hours Out of Class 14 7 98
Midterms 1 20 20
Final 1 30 30
Total Workload 204

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) Utilize the wealth of information stored in computer databases to answer basic biological questions and solve problems such as diagnosis and treatment of diseases. 5
2) Acquire an ability to compile and analyze biological information, clearly present and discuss the conclusions, the inferred knowledge and the arguments behind them both in oral and written format. 5
3) Develop critical, creative and analytical thinking skills. 4
4) Develop effective communication skills and have competence in scientific speaking, reading and writing abilities in English and Turkish. 4
5) Gain knowledge of different techniques and methods used in genetics and acquire the relevant laboratory skills. 4
6) Detect biological problems, learn to make hypothesis and solve the hypothesis by using variety of experimental and observational methods. 3
7) Gain knowledge of methods for collecting quantitative and qualitative data and obtain the related skills. 3
8) Conduct research through paying attention to ethics, human values and rights. Pay special attention to confidentiality of information while working with human subjects. 3
9) Obtain basic concepts used in theory and practices of molecular biology and genetics and establish associations between them. 5
10) Search and use literature to improve himself/herself and follow recent developments in science and technology. 2
11) Be aware of the national and international problems in the field and search for solutions. 3