MOLECULAR BIOLOGY AND GENETICS | |||||
Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 |
Course Code | Course Name | Semester | Theoretical | Practical | Credit | ECTS |
BNG5113 | Cellular and Molecular Bioengineering | Spring | 3 | 0 | 3 | 8 |
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester. |
Language of instruction: | English |
Type of course: | Departmental Elective |
Course Level: | Bachelor’s Degree (First Cycle) |
Mode of Delivery: | Face to face |
Course Coordinator : | Prof. Dr. GÜLAY BULUT |
Recommended Optional Program Components: | There is none. |
Course Objectives: | The molecular and cellular bases of life from an engineering perspective. Analysis and engineering of biomolecular structure and dynamics, enzyme function, molecular interactions, metabolic pathways, signal transduction, and cellular mechanics. |
The students who have succeeded in this course; 1) Discuss molecular and cellular bases of life through bioengineering perspective. 2) Learn biomolecular structure and dynamics. 3) Learn enzyme function and dynamics. 4) Discuss metabolic pathways and signal transduction. |
This course investigates the molecules and mechanisms underlying cellular function from an engineering perspective, utilizing physical, chemical and quantitative approaches. |
Week | Subject | Related Preparation |
1) | DNA replication | |
2) | DNA elasticity | |
3) | DNA sequencing technologies I | |
4) | DNA sequencing technologies II | |
5) | Melting and other structural transitions in DNA | |
6) | DNA nanotechnology | |
7) | Driving forces in protein folding and binding I | |
8) | Driving forces in protein folding and binding II | |
9) | Allostery | |
10) | Protein design I | |
11) | Protein design II | |
12) | Metabolic engineering | |
13) | Synthetic biology I | |
14) | Synthetic biology II |
Course Notes / Textbooks: | Griffiths, J. B., 1990. Animal Cell Biotechnology, Vol 1-4; Eds. R. E. Spier, Acad. Pres Inc. Freshney I. R. 1994. Culture of Animal Cells. Wiley Liss Inc. Neumann, K., H., A.Kumar, J. Imani, 2009. Plant Cell and Tissue Culture – A Tool in Biotechnology; Basics and Application. Springer – Verlag , Berlin Heidelberg. George, E. F., M.A. Hall, G.-J.De Klerk, 2008. Plant Propagation by Tissue Culture. 3rd Edition Volume 1. Springer Publishing Company. Loyola-Vargas, V.M., F. Vázquez-Flota, 2006. Plant Cell Culture Protocols, Second Edition, Humana Press Inc. Bailey, J. E., D. F. Ollis, 1986. Biochemical Engineering Fundamentals, McGraw Hill. |
References: | Related articles. İlgili makaleler. |
Semester Requirements | Number of Activities | Level of Contribution |
Attendance | 1 | % 10 |
Midterms | 1 | % 30 |
Final | 1 | % 60 |
Total | % 100 | |
PERCENTAGE OF SEMESTER WORK | % 40 | |
PERCENTAGE OF FINAL WORK | % 60 | |
Total | % 100 |
Activities | Number of Activities | Duration (Hours) | Workload |
Course Hours | 14 | 4 | 56 |
Study Hours Out of Class | 14 | 7 | 98 |
Midterms | 1 | 20 | 20 |
Final | 1 | 30 | 30 |
Total Workload | 204 |
No Effect | 1 Lowest | 2 Low | 3 Average | 4 High | 5 Highest |
Program Outcomes | Level of Contribution | |
1) | Utilize the wealth of information stored in computer databases to answer basic biological questions and solve problems such as diagnosis and treatment of diseases. | 5 |
2) | Acquire an ability to compile and analyze biological information, clearly present and discuss the conclusions, the inferred knowledge and the arguments behind them both in oral and written format. | 5 |
3) | Develop critical, creative and analytical thinking skills. | 5 |
4) | Develop effective communication skills and have competence in scientific speaking, reading and writing abilities in English and Turkish. | 4 |
5) | Gain knowledge of different techniques and methods used in genetics and acquire the relevant laboratory skills. | 4 |
6) | Detect biological problems, learn to make hypothesis and solve the hypothesis by using variety of experimental and observational methods. | 5 |
7) | Gain knowledge of methods for collecting quantitative and qualitative data and obtain the related skills. | 3 |
8) | Conduct research through paying attention to ethics, human values and rights. Pay special attention to confidentiality of information while working with human subjects. | 3 |
9) | Obtain basic concepts used in theory and practices of molecular biology and genetics and establish associations between them. | 4 |
10) | Search and use literature to improve himself/herself and follow recent developments in science and technology. | 4 |
11) | Be aware of the national and international problems in the field and search for solutions. | 4 |