BNG5113 Cellular and Molecular BioengineeringBahçeşehir UniversityDegree Programs MOLECULAR BIOLOGY AND GENETICSGeneral Information For StudentsDiploma SupplementErasmus Policy StatementNational QualificationsBologna Commission
MOLECULAR BIOLOGY AND GENETICS
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
BNG5113 Cellular and Molecular Bioengineering Spring 3 0 3 8
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction: English
Type of course: Departmental Elective
Course Level: Bachelor’s Degree (First Cycle)
Mode of Delivery: Face to face
Course Coordinator : Prof. Dr. GÜLAY BULUT
Recommended Optional Program Components: There is none.
Course Objectives: The molecular and cellular bases of life from an engineering perspective. Analysis and engineering of biomolecular structure and dynamics, enzyme function, molecular interactions, metabolic pathways, signal transduction, and cellular mechanics.

Learning Outcomes

The students who have succeeded in this course;
1) Discuss molecular and cellular bases of life through bioengineering perspective.
2) Learn biomolecular structure and dynamics.
3) Learn enzyme function and dynamics.
4) Discuss metabolic pathways and signal transduction.

Course Content

This course investigates the molecules and mechanisms underlying cellular function from an engineering perspective, utilizing physical, chemical and quantitative approaches.

Weekly Detailed Course Contents

Week Subject Related Preparation
1) DNA replication
2) DNA elasticity
3) DNA sequencing technologies I
4) DNA sequencing technologies II
5) Melting and other structural transitions in DNA
6) DNA nanotechnology
7) Driving forces in protein folding and binding I
8) Driving forces in protein folding and binding II
9) Allostery
10) Protein design I
11) Protein design II
12) Metabolic engineering
13) Synthetic biology I
14) Synthetic biology II

Sources

Course Notes / Textbooks: Griffiths, J. B., 1990. Animal Cell Biotechnology, Vol 1-4; Eds. R. E. Spier, Acad. Pres Inc. Freshney I. R. 1994. Culture of Animal Cells. Wiley Liss Inc. Neumann, K., H., A.Kumar, J. Imani, 2009. Plant Cell and Tissue Culture – A Tool in Biotechnology; Basics and Application. Springer – Verlag , Berlin Heidelberg. George, E. F., M.A. Hall, G.-J.De Klerk, 2008. Plant Propagation by Tissue Culture. 3rd Edition Volume 1. Springer Publishing Company. Loyola-Vargas, V.M., F. Vázquez-Flota, 2006. Plant Cell Culture Protocols, Second Edition, Humana Press Inc. Bailey, J. E., D. F. Ollis, 1986. Biochemical Engineering Fundamentals, McGraw Hill.
References: Related articles.
İlgili makaleler.

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Attendance 1 % 10
Midterms 1 % 30
Final 1 % 60
Total % 100
PERCENTAGE OF SEMESTER WORK % 40
PERCENTAGE OF FINAL WORK % 60
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 4 56
Study Hours Out of Class 14 7 98
Midterms 1 20 20
Final 1 30 30
Total Workload 204

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) Utilize the wealth of information stored in computer databases to answer basic biological questions and solve problems such as diagnosis and treatment of diseases. 5
2) Acquire an ability to compile and analyze biological information, clearly present and discuss the conclusions, the inferred knowledge and the arguments behind them both in oral and written format. 5
3) Develop critical, creative and analytical thinking skills. 5
4) Develop effective communication skills and have competence in scientific speaking, reading and writing abilities in English and Turkish. 4
5) Gain knowledge of different techniques and methods used in genetics and acquire the relevant laboratory skills. 4
6) Detect biological problems, learn to make hypothesis and solve the hypothesis by using variety of experimental and observational methods. 5
7) Gain knowledge of methods for collecting quantitative and qualitative data and obtain the related skills. 3
8) Conduct research through paying attention to ethics, human values and rights. Pay special attention to confidentiality of information while working with human subjects. 3
9) Obtain basic concepts used in theory and practices of molecular biology and genetics and establish associations between them. 4
10) Search and use literature to improve himself/herself and follow recent developments in science and technology. 4
11) Be aware of the national and international problems in the field and search for solutions. 4