BME4506 Cell and Tissue EngineeringBahçeşehir UniversityDegree Programs BIOMEDICAL ENGINEERING (ENGLISH, THESIS)General Information For StudentsDiploma SupplementErasmus Policy StatementBologna CommissionNational Qualifications
BIOMEDICAL ENGINEERING (ENGLISH, THESIS)
Master TR-NQF-HE: Level 7 QF-EHEA: Second Cycle EQF-LLL: Level 7

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
BME4506 Cell and Tissue Engineering Fall
Spring
2 2 3 7
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction: English
Type of course: Departmental Elective
Course Level:
Mode of Delivery: Face to face
Course Coordinator : Assist. Prof. CANAN BAĞCI
Course Objectives: Upon successful completion of this course, the student will be able to:

- Describe the principals of cell and tissue engineering
- Describe the fundamental patterns of growth and differentiation
- Explain the concepts of in vitro control of tissue development
- Explain the concepts of in vivo synthesis of tissues and organs
- Define different types of biomaterials used in tissue engineering
- Describe the transplantation process for engineered cells and tissues.
- Explain the stem cell and gene therapy concepts.

Learning Outcomes

The students who have succeeded in this course;
- Describe the principals of cell and tissue engineering
- Describe the fundamental patterns of growth and differentiation
- Explain the concepts of in vitro control of tissue development
- Explain the concepts of in vivo synthesis of tissues and organs
- Define different types of biomaterials used in tissue engineering
- Describe the transplantation process for engineered cells and tissues.
- Explain the stem cell and gene therapy concepts.

Course Content

This course provides an in-depth introduction to the principles of cell and tissue engineering, covering fundamental concepts of cell growth, differentiation, and tissue development. Students will explore in vitro and in vivo approaches to tissue synthesis, the role of biomaterials, and transplantation techniques, stem cell applications, gene therapy, and emerging trends such as 3D bioprinting and regenerative medicine.

Teaching methods and techniques used in the course are lecture, reading, discussion, individual study, student presentations and laboratory experiments.

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Introduction to Cell and Tissue Engineering Lecture Notes
2) The Basis of Growth and Differentiation -1 Lecture Notes
3) The Basis of Growth and Differentiation -2 Lecture Notes
4) In vitro Control of Tissue Development Lecture Notes
5) In vivo Synthesis of Tissues and Organs - 1 / Lab session #1 Basic information about cell culture lab Lecture Notes
6) In vivo Synthesis of Tissues and Organs - 2 / Lab session #2 Pipetting, handling of the equipments Lecture Notes
7) Biomaterials in Tissue Engineering - 1 / Lab session #3 Cell counting, changing the media Lecture Notes
8) Biomaterials in Tissue Engineering -2 Lecture Notes
9) Biomaterials in Tissue Engineering - 3 / Lab session #4 Subculturing Lecture Notes
10) Transplantation of Engineered Cells and Tissues / Lab session #5 MTT cytotoxicity assay Lecture Notes
11) Stem Cells / Lab session #6 Biocompatible scaffolds Lecture Notes
12) Gene Therapy Lecture Notes
13) Student Presentations
14) Student Presentations

Sources

Course Notes / Textbooks: 1. Ders notları
2. Principles of Tissue Engineering, Robert Lanza, Robert Langer, Joseph Vacanti, Anthony Atala. 5th edition.
References: 1. Lecture Notes
2. Principles of Tissue Engineering, Robert Lanza, Robert Langer, Joseph Vacanti, Anthony Atala. 5th edition.

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Laboratory 6 % 15
Presentation 1 % 15
Midterms 1 % 30
Final 1 % 40
Total % 100
PERCENTAGE OF SEMESTER WORK % 60
PERCENTAGE OF FINAL WORK % 40
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 2 28
Laboratory 6 2 12
Study Hours Out of Class 14 8 112
Presentations / Seminar 1 8 8
Midterms 1 1 1
Final 1 1 1
Total Workload 162

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution