MOLECULAR BIOLOGY AND GENETICS
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Course Introduction and Application Information

Course Code	Course Name	Semester	Theoretical	Practical	Credit	ECTS
BME2063	Biomaterials	Spring	3	0	3	5

This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction:	English
Type of course:	Non-Departmental Elective
Course Level:	Bachelor’s Degree (First Cycle)
Mode of Delivery:	Face to face
Course Coordinator :	Dr. Öğr. Üyesi İREM DEMİRKAN
Course Lecturer(s):	Dr. Öğr. Üyesi BURCU TUNÇ ÇAMLIBEL
Recommended Optional Program Components:	None
Course Objectives:	The goal of this course is, - to teach what the field of biomaterials encompasses, - to review principles from general chemistry, - to teach the chemistry and engineering skills needed to solve challenges in the biomaterials and tissue engineering area - to teach the types of biomaterials, the interactions between the body tissues and biocompatible materials, the production techniques, and the future trends

Learning Outcomes

The students who have succeeded in this course;
- The students who have succeeded in this course will;
1) Understand the fundamental properties of biomaterials and biocompatibility,
2) Understand different types of bonding and how these are oganized into material subunits for metal, ceramics and polymers,
3) Understand the molecular mechanisms behind the mechanical properies for each class of materials as well as the principles behind the events that stengthen and weaken biomaterials,
4) Understand the surface properties, toxicity and material characterization techniques,
5) Understand molecular mechanisms behind environmental degradation of metals, ceramics, and polymers in the human body.
6) Understand why the study of biomaterials is an important aspect of the educational background of the biomedical engineer, and be able to make research and present their studies related to biomaterials science.

Course Content

Basic concepts of biomaterials science, the structure of metals, ceramics, polymers and composite biomaterials, biocompatibility, corrosion and degradation of biomaterials, surface properties of biomaterials.

Weekly Detailed Course Contents

Week	Subject	Related Preparation
1)	Introduction to basic concepts of biomaterials sciences and classes of materials used in medicine	none
2)	Atomic Structure and Interatomic Bonding	None
3)	The Structure of Crystalline Solids	None
4)	Imperfections in Solids, Diffusion	None
5)	Mechanical Properties of Metals	None
6)	Dislocations and Strengthening Mechanisms
7)	Failure, Phase Diagrams	None
8)	Applications and Processing of Metal Alloys, Metallic Implant Materials	None
9)	Structure and Characteristics of Ceramics, Applications and Processing of Ceramic, Ceramic Implant Materials	None
10)	Polymer Structures, Characteristics, Applications and Processing, Polymeric Implant Materials	None
11)	Composites as Biomaterials	None
12)	Surface Properties of Biomaterials and Material Characterization Methods	None
13)	Corrosion and Degradation of Biomaterials, Electrical Properties, Magnetic Properties, Thermal Properties, Optical Properties	None
14)	Biocompatibility and biocompatibility Testing of Biomaterials

Sources

Course Notes / Textbooks:	Biomaterials Science: An Introduction to Materials in medicine", Rattner BD, Hoffman AS, Schoen FJ, and Lemons JE, eds., 2nd ed., Elsevier Academic Press, San Diego, CA, 2004.
References:	Biomaterials, an Introduction by Park and Lakes, Springer, Third ed., 2007 Biomaterials, The Intersection of Biology and Materials Science by Temenoff and Mikos, Pearson, 2008

Evaluation System

Semester Requirements	Number of Activities	Level of Contribution
Project	1	% 30
Midterms	1	% 30
Final	1	% 40
Total		% 100
PERCENTAGE OF SEMESTER WORK		% 30
PERCENTAGE OF FINAL WORK		% 70
Total		% 100

ECTS / Workload Table

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	3	42
Study Hours Out of Class	14	4	56
Presentations / Seminar	1	1	1
Project	1	27	27
Midterms	1	2	2
Final	1	2	2
Total Workload			130

Contribution of Learning Outcomes to Programme Outcomes

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Utilize the wealth of information stored in computer databases to answer basic biological questions and solve problems such as diagnosis and treatment of diseases.	3
2)	Acquire an ability to compile and analyze biological information, clearly present and discuss the conclusions, the inferred knowledge and the arguments behind them both in oral and written format.	4
3)	Develop critical, creative and analytical thinking skills.	5
4)	Develop effective communication skills and have competence in scientific speaking, reading and writing abilities in English and Turkish.	3
5)	Gain knowledge of different techniques and methods used in genetics and acquire the relevant laboratory skills.	4
6)	Detect biological problems, learn to make hypothesis and solve the hypothesis by using variety of experimental and observational methods.	4
7)	Gain knowledge of methods for collecting quantitative and qualitative data and obtain the related skills.	3
8)	Conduct research through paying attention to ethics, human values and rights. Pay special attention to confidentiality of information while working with human subjects.	5
9)	Obtain basic concepts used in theory and practices of molecular biology and genetics and establish associations between them.	4
10)	Search and use literature to improve himself/herself and follow recent developments in science and technology.	5
11)	Be aware of the national and international problems in the field and search for solutions.	4