LOGISTIC MANAGEMENT | |||||
Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 |
Course Code | Course Name | Semester | Theoretical | Practical | Credit | ECTS |
GEN4059 | Computational Methods in Bioinformatics | Fall | 3 | 0 | 3 | 6 |
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester. |
Language of instruction: | English |
Type of course: | Non-Departmental Elective |
Course Level: | Bachelor’s Degree (First Cycle) |
Mode of Delivery: | Face to face |
Course Coordinator : | Dr. Öğr. Üyesi ELIZABETH HEMOND |
Recommended Optional Program Components: | There is none. |
Course Objectives: | The goal of this course is to provide an understanding of the fundamental computational methods used in bioinformatics and set of algorithms that have important applications in bioinformatics and also have several other applications outside of bioinformatics. |
The students who have succeeded in this course; 1. Recognize the fundamental models of computation useful in modeling nucleic acid and protein sequences. 2. Design and implement algorithms useful for analyzing various molecular biology data. 3. Discuss Genetic Algorithm and its applications in bioinformatics. 4. Discuss Greedy Algorithms and its applications in bioinformatics. 5. Discuss Gibbs sampling and its applications in bioinformatics. 6. Recognize Expectation Maximization and its applications in bioinformatics. 7. Recognize Hidden Markov models and its applications in bioinformatics. 8. Define Bayesian networks and its applications in bioinformatics. 9. Define graphs and its applications in bioinformatics. |
This course will provide a broad and through background in computational methods and algorithms that are widely used in bioinformatics applications. Various existing methods will be critically described and the strengths and limitations of each will be discussed. |
Week | Subject | Related Preparation |
1) | A brief introduction to computational complexity and algorithm design techniques | |
2) | Exact sequence search algorithms | |
3) | Rabin-Karp algorithm, pattern matching, suffix trees | |
4) | Elements of dynamic programming, Manhattan tourist problem, k-band algorithm | |
5) | Approximate string matching, divide and conquer algorithms | |
6) | Branch and bound search | |
7) | Genetic Algorithm | |
8) | Greedy Algorithms | |
9) | Gibbs sampling | |
10) | Expectation Maximization | |
11) | Hidden Markov models | |
12) | Bayesian networks | |
13) | Graphs | |
14) | Review |
Course Notes / Textbooks: | Relevant course notes or hand-outs will be supplied. |
References: | 1)An Introduction to Bioinformatics Algorithms (Computational Molecular Biology), Neil Jones and Pavel Pevzner, MIT Press, 2004. |
Semester Requirements | Number of Activities | Level of Contribution |
Homework Assignments | 2 | % 10 |
Project | 1 | % 25 |
Midterms | 1 | % 25 |
Final | 1 | % 40 |
Total | % 100 | |
PERCENTAGE OF SEMESTER WORK | % 35 | |
PERCENTAGE OF FINAL WORK | % 65 | |
Total | % 100 |
Activities | Number of Activities | Duration (Hours) | Workload |
Course Hours | 14 | 3 | 42 |
Study Hours Out of Class | 14 | 7 | 98 |
Midterms | 1 | 2 | 2 |
Final | 1 | 2 | 2 |
Total Workload | 144 |
No Effect | 1 Lowest | 2 Low | 3 Average | 4 High | 5 Highest |
Program Outcomes | Level of Contribution | |
1) | To correctly identify the problems and to be able to ask the correct questions | |
2) | To have the ability for problem solving and to utilize analytical approach in dealing with the problems | |
3) | To be able to identify business processes and use them to increase the productivity in logistics system. | |
4) | To be fully prepared for a graduate study | 2 |
5) | Awareness of the new advancements in Information and Communications Technologies (ICT) and to be able to use them in logistics management effectively. internet and the electronic world | |
6) | To understand the components of logistics as well as the importance of the coordination among these components. | |
7) | To know the necessary ingredients for improving the productivity in business life | |
8) | To think innovatively and creatively in complex situations | 4 |
9) | To act and think both regionally and internationally | |
10) | To understand the demands and particular questions of globalization | |
11) | Aware of the two way interaction between globalization and logistics; as well as to use this interaction for increasing the productivity. | |
12) | To be able to use at least one foreign language both for communication and academic purposes | 2 |
13) | To acquire leadership qualities but also to know how to be a team member | |
14) | To understand the importance of business ethics and to apply business ethics as a principal guide in both business and academic environment |