LOGISTICS (TURKISH)
Associate	TR-NQF-HE: Level 5	QF-EHEA: Short Cycle	EQF-LLL: Level 5

Course Introduction and Application Information

Course Code	Course Name	Semester	Theoretical	Practical	Credit	ECTS
MBG4066	Cancer Genetics and Biology	Fall	3	0	3	6

This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction:	English
Type of course:	Non-Departmental Elective
Course Level:	Associate (Short Cycle)
Mode of Delivery:	Face to face
Course Coordinator :	Dr. Öğr. Üyesi ELIZABETH HEMOND
Course Objectives:	In this course, student should learn about genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Learning Outcomes

The students who have succeeded in this course;
1. Have a general knowledge on genetic changes induced by cancer.
2. Discuss terms of oncogene and tumor suppressor gene.
3. Understand hereditary cancers and DNA repair cancer relationship.
4. Discuss cell cycle, apoptosis and multicellular cell interactions in cancer.

Course Content

Genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Weekly Detailed Course Contents

Week	Subject	Related Preparation
1)	Cancer as a disease
2)	Model organisms and techniques used in cancer studies
3)	Mutated genomes of cancer cells, DNA gains, DNA losses and nucleotide changes
4)	Epigenetic changes in cancer cells
5)	Viral and cellular oncogenes
6)	Tumor suppressor genes
7)	Overview of phenotypic changes in cancer cells
8)	Cell cycle and cancer
9)	DNA damage response in cancer cells
10)	DNA repair and cancer
11)	Senescence aberrations in cancer cells
12)	Apoptotic and autophagic aberrations in cancer cells
13)	Invasive and metastatic abilities of cancer cells
14)	Tumor heterogeneity and "cancer stem cells"

Sources

Course Notes / Textbooks:	The Molecular Basis of Cancer.2nd edition Author(s): Mendelsohn, Howley, Israel & Liotta. Publisher: W. B. Saunders Company, Philadelphia, 2011
References:	The Genetic Basis of Human Cancer Author(s): B. Vogelstein & K. W. Kinzler Publisher: McGraw-Hill, New York, 1999

Evaluation System

Semester Requirements	Number of Activities	Level of Contribution
Attendance	10	% 5
Homework Assignments	1	% 15
Midterms	1	% 30
Final	1	% 50
Total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
Total		% 100

ECTS / Workload Table

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	3	42
Study Hours Out of Class	14	8	112
Midterms	1	2	2
Final	1	2	2
Total Workload			158

Contribution of Learning Outcomes to Programme Outcomes

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	To have knowledge about logistics operations and the basic legislation
2)	To have knowledge about the politics, corporations and the developments in logistics.
3)	To have knowledge about the economical life and the basic features of the enterprises that take place in logistics sector.
4)	To have knowledge about the documents that are used in logistics and how to prepare them.
5)	To have knowledge about the new marketing and sales techniques and the principles of opening to new markets.
6)	To have knowledge and consciousness about the job security, worker health and environment protection in logistics sector.
7)	To have knowledge and consciousness about the basic legal attainments, social responsibility, ethics and social security rights in logistics.
8)	To be involved in communication network in logistics sector and follow the developments.	2
9)	To have the ability to comment and evaluate the classical and current theories by taking into account the developments in logistics and supply chain areas.
10)	To have the basic knowledge about foreign trade and customs legislation.
11)	To have knowledge about relationship between foreign trade and logistics management.
12)	To have basic knowledge in at least one foreign language.
13)	He/she can use information and communication tecnologies that necessary for their area, follows technological change and applies new technologies to business system.