MECHATRONICS (TURKISH) | |||||
Associate | TR-NQF-HE: Level 5 | QF-EHEA: Short Cycle | EQF-LLL: Level 5 |
Course Code | Course Name | Semester | Theoretical | Practical | Credit | ECTS |
MBG4066 | Cancer Genetics and Biology | Spring Fall |
3 | 0 | 3 | 6 |
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester. |
Language of instruction: | English |
Type of course: | Non-Departmental Elective |
Course Level: | Associate (Short Cycle) |
Mode of Delivery: | Face to face |
Course Coordinator : | Dr. Öğr. Üyesi ELIZABETH HEMOND |
Course Objectives: | In this course, student should learn about genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer. |
The students who have succeeded in this course; 1. Have a general knowledge on genetic changes induced by cancer. 2. Discuss terms of oncogene and tumor suppressor gene. 3. Understand hereditary cancers and DNA repair cancer relationship. 4. Discuss cell cycle, apoptosis and multicellular cell interactions in cancer. |
Genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer. |
Week | Subject | Related Preparation |
1) | Cancer as a disease | |
2) | Model organisms and techniques used in cancer studies | |
3) | Mutated genomes of cancer cells, DNA gains, DNA losses and nucleotide changes | |
4) | Epigenetic changes in cancer cells | |
5) | Viral and cellular oncogenes | |
6) | Tumor suppressor genes | |
7) | Overview of phenotypic changes in cancer cells | |
8) | Cell cycle and cancer | |
9) | DNA damage response in cancer cells | |
10) | DNA repair and cancer | |
11) | Senescence aberrations in cancer cells | |
12) | Apoptotic and autophagic aberrations in cancer cells | |
13) | Invasive and metastatic abilities of cancer cells | |
14) | Tumor heterogeneity and "cancer stem cells" |
Course Notes / Textbooks: | The Molecular Basis of Cancer.2nd edition Author(s): Mendelsohn, Howley, Israel & Liotta. Publisher: W. B. Saunders Company, Philadelphia, 2011 |
References: | The Genetic Basis of Human Cancer Author(s): B. Vogelstein & K. W. Kinzler Publisher: McGraw-Hill, New York, 1999 |
Semester Requirements | Number of Activities | Level of Contribution |
Attendance | 10 | % 5 |
Homework Assignments | 1 | % 15 |
Midterms | 1 | % 30 |
Final | 1 | % 50 |
Total | % 100 | |
PERCENTAGE OF SEMESTER WORK | % 50 | |
PERCENTAGE OF FINAL WORK | % 50 | |
Total | % 100 |
Activities | Number of Activities | Duration (Hours) | Workload |
Course Hours | 14 | 3 | 42 |
Study Hours Out of Class | 14 | 8 | 112 |
Midterms | 1 | 2 | 2 |
Final | 1 | 2 | 2 |
Total Workload | 158 |
No Effect | 1 Lowest | 2 Low | 3 Average | 4 High | 5 Highest |
Program Outcomes | Level of Contribution | |
1) | To improve fundamental computer knowledge, to encourage students using office and package programs. | |
2) | Ability to have and use of fundamental mathematics knowledge and skills the usage of relevant materials. | |
3) | Ability to recognize general structures of machine equipments and the features of shaping | |
4) | Ability to grasp manufacturing processes and cutting tool materials, materials, statics, mechanics and fluid science fundemantal knowledge. | |
5) | Ability to draw assembly and auxilary devices as well as to draw whole or details of a system. | |
6) | Ability to have a knowledge of fundemantal manufacturing process such as turning, milling, punching,grinding and welding techniques and to have a self esteem in order to work behind the bench. | |
7) | Ability to do computer aided design and write program on digital benches. | |
8) | Ability to prepare project report, follow up project process and implement projects. | |
9) | ability to learn the areas of usage of electronic circuit components. Ability to grasp and write programs for micro controllers and for their components. Ability to design relevant circuits. | |
10) | Ability to understand the electric motors principles and AC-DC analysis | |
11) | Ability to gain a dominaion on visual programming | |
12) | Having the ability to communicate efficiently in verbal and written Turkish, to know at least one foreign language in order to communicate with the colleagues and customers. |