COMPUTER PROGRAMMING (TURKISH)
Associate	TR-NQF-HE: Level 5	QF-EHEA: Short Cycle	EQF-LLL: Level 5

Course Introduction and Application Information

Course Code	Course Name	Semester	Theoretical	Practical	Credit	ECTS
MBG4066	Cancer Genetics and Biology	Spring Fall	3	0	3	6

This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction:	English
Type of course:	Non-Departmental Elective
Course Level:	Associate (Short Cycle)
Mode of Delivery:	Face to face
Course Coordinator :	Dr. Öğr. Üyesi ELIZABETH HEMOND
Course Objectives:	In this course, student should learn about genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Learning Outcomes

The students who have succeeded in this course;
1. Have a general knowledge on genetic changes induced by cancer.
2. Discuss terms of oncogene and tumor suppressor gene.
3. Understand hereditary cancers and DNA repair cancer relationship.
4. Discuss cell cycle, apoptosis and multicellular cell interactions in cancer.

Course Content

Genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Weekly Detailed Course Contents

Week	Subject	Related Preparation
1)	Cancer as a disease
2)	Model organisms and techniques used in cancer studies
3)	Mutated genomes of cancer cells, DNA gains, DNA losses and nucleotide changes
4)	Epigenetic changes in cancer cells
5)	Viral and cellular oncogenes
6)	Tumor suppressor genes
7)	Overview of phenotypic changes in cancer cells
8)	Cell cycle and cancer
9)	DNA damage response in cancer cells
10)	DNA repair and cancer
11)	Senescence aberrations in cancer cells
12)	Apoptotic and autophagic aberrations in cancer cells
13)	Invasive and metastatic abilities of cancer cells
14)	Tumor heterogeneity and "cancer stem cells"

Sources

Course Notes / Textbooks:	The Molecular Basis of Cancer.2nd edition Author(s): Mendelsohn, Howley, Israel & Liotta. Publisher: W. B. Saunders Company, Philadelphia, 2011
References:	The Genetic Basis of Human Cancer Author(s): B. Vogelstein & K. W. Kinzler Publisher: McGraw-Hill, New York, 1999

Evaluation System

Semester Requirements	Number of Activities	Level of Contribution
Attendance	10	% 5
Homework Assignments	1	% 15
Midterms	1	% 30
Final	1	% 50
Total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
Total		% 100

ECTS / Workload Table

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	3	42
Study Hours Out of Class	14	8	112
Midterms	1	2	2
Final	1	2	2
Total Workload			158

Contribution of Learning Outcomes to Programme Outcomes

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Students will have knowledge of fundemantals of mathemetaics and phsics
2)	Students will have konowledge of relevant software and hardware requirements in the office environment
3)	Having the ability to define and explain the fundemental concepts, principles and essentilas of software and having the ability to develop software.
4)	Having the ability to use tools, machines and having the ability to recognize and diagnose problems in the related computer fields.
5)	Having the ability to communicate efficiently in verbal and written Turkish, to know at least one foreign language in order to communicate with the colleagues and customers.
6)	Having the ability to setup,diagnose and maintanance of databases
7)	Having the ability to design graphical animations for desktop applications and internet programming.
8)	Having the ability to develop and control internet projects
9)	Having the ability to develop group projects, team work, software and hardware projects
10)	Having the ability to set up,diagnose operating systems and network systems