MBG4066 Cancer Genetics and BiologyBahçeşehir UniversityDegree Programs ECONOMICS AND FINANCEGeneral Information For StudentsDiploma SupplementErasmus Policy StatementNational QualificationsBologna Commission
ECONOMICS AND FINANCE
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
MBG4066 Cancer Genetics and Biology Spring 3 0 3 6
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction: English
Type of course: Non-Departmental Elective
Course Level: Bachelor’s Degree (First Cycle)
Mode of Delivery: Face to face
Course Coordinator : Dr. Öğr. Üyesi ELIZABETH HEMOND
Course Objectives: In this course, student should learn about genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Learning Outcomes

The students who have succeeded in this course;
1. Have a general knowledge on genetic changes induced by cancer.
2. Discuss terms of oncogene and tumor suppressor gene.
3. Understand hereditary cancers and DNA repair cancer relationship.
4. Discuss cell cycle, apoptosis and multicellular cell interactions in cancer.

Course Content

Genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Cancer as a disease
2) Model organisms and techniques used in cancer studies
3) Mutated genomes of cancer cells, DNA gains, DNA losses and nucleotide changes
4) Epigenetic changes in cancer cells
5) Viral and cellular oncogenes
6) Tumor suppressor genes
7) Overview of phenotypic changes in cancer cells
8) Cell cycle and cancer
9) DNA damage response in cancer cells
10) DNA repair and cancer
11) Senescence aberrations in cancer cells
12) Apoptotic and autophagic aberrations in cancer cells
13) Invasive and metastatic abilities of cancer cells
14) Tumor heterogeneity and "cancer stem cells"

Sources

Course Notes / Textbooks: The Molecular Basis of Cancer.2nd edition Author(s): Mendelsohn, Howley, Israel & Liotta. Publisher: W. B. Saunders Company, Philadelphia, 2011
References: The Genetic Basis of Human Cancer Author(s): B. Vogelstein & K. W. Kinzler Publisher: McGraw-Hill, New York, 1999

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Attendance 10 % 5
Homework Assignments 1 % 15
Midterms 1 % 30
Final 1 % 50
Total % 100
PERCENTAGE OF SEMESTER WORK % 50
PERCENTAGE OF FINAL WORK % 50
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 3 42
Study Hours Out of Class 14 8 112
Midterms 1 2 2
Final 1 2 2
Total Workload 158

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) Build up a body of knowledge in mathematics and statistics, to use them, to understand how the mechanism of economy –both at micro and macro levels – works. 3
2) Understand the common as well as distinctive characters of the markets, industries, market regulations and policies. 2
3) Develop an awareness of different approaches to the economic events and why and how those approaches have been formed through the Economic History and understand the differences among those approaches by noticing at what extent they could explain the economic events. 1
4) Analyze the interventions of politics to the economics and vice versa. 3
5) Apply the economic analysis to everyday economic problems and evaluate the policy proposals for those problems by comparing opposite approaches. 2
6) Understand current and new economic events and how the new approaches to the economics are formed and evaluating. 2
7) Develop the communicative skills in order to explain the specific economic issues/events written, spoken and graphical form. 3
8) Know how to formulate the economics problems and issues and define the solutions in a well-formed written form, which includes the hypothesis, literature, methodology and results / empirical evidence. 2
9) Demonstrate the quantitative and qualitative capabilities and provide evidence for the hypotheses and economic arguments. 2
10) Understand the information and changes related to the economy by using a foreign language and communicate with colleagues. 3