MBG4065 Introduction to Stem CellsBahçeşehir UniversityDegree Programs ARCHITECTUREGeneral Information For StudentsDiploma SupplementErasmus Policy StatementNational QualificationsBologna Commission
ARCHITECTURE
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
MBG4065 Introduction to Stem Cells Spring
Fall
3 0 3 6
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction: English
Type of course: Non-Departmental Elective
Course Level: Bachelor’s Degree (First Cycle)
Mode of Delivery: Face to face
Course Coordinator : Dr. Öğr. Üyesi ELIZABETH HEMOND
Course Objectives: In this course, student should learn about the basic biology of embryonic, adult and cancer stem cells, molecular mechanisms of self renewal, differentiation and plasticity, reproductive and therapeutic cloning, epigenetic changes associated with stem cells, use of stem cells in cell based therapies and its ethical considerations.

Learning Outcomes

The students who have succeeded in this course;
1. Have a general understanding on stem cell biology.
2. Learn the basic features of stem cells and discuss the related mechanisms beneath.
3. Understand the effects of stem cells on the epigenetic changes.
4. Discuss stem cell based therapies and the related ethical issues stem from the uses of those therapies.
5. Categorize the stem cells.

Course Content

Basic biology of embryonic, adult and cancer stem cells. Molecular mechanisms of self renewal, differentiation and plasticity. Reproductive and therapeutic cloning. Epigenetic changes associated with stem cells. Use of stem cells in cell based therapies and its ethical considerations.

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Introduction and classification of stem cells
2) Basic biology of stem cells (self-renewal, pluripotency, plasticity, asymmetric division, niche)
3) Embryonic Stem Cells
4) Epiblast Stem Cells
5) Induced Pluripotent Stem Cells
6) Germline Stem Cells, Epigenetic Reprogramming I
7) Germline Stem Cells, Epigenetic Reprogramming II
8) Cancer Stem Cells
9) Mesenchymal Stem Cells
10) Hematopoeitic stem cells
11) Organ Specific Stem Cells (Neural- Vascular Endothelial, Pancreatic)
12) Organ Specific Stem Cells (Hepatic, Cardiac)
13) Organ Specific Stem Cells (Epidermal, Lung)
14) Review

Sources

Course Notes / Textbooks: Weekly course notes will be provided
References: Stem Cells Handbook, Steward Sell Publisher, 2003,ISBN 13: 9781588291134

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Attendance 10 % 5
Homework Assignments 1 % 15
Midterms 1 % 30
Final 1 % 50
Total % 100
PERCENTAGE OF SEMESTER WORK % 50
PERCENTAGE OF FINAL WORK % 50
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 3 42
Study Hours Out of Class 14 8 112
Midterms 1 2 2
Final 1 2 2
Total Workload 158

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) Using the theoretical/conceptual and practical knowledge acquired for architectural design, design activities and research.
2) Identifying, defining and effectively discussing aesthetic, functional and structural requirements for solving design problems using critical thinking methods.
3) Being aware of the diversity of social patterns and user needs, values and behavioral norms, which are important inputs in the formation of the built environment, at local, regional, national and international scales.
4) Gaining knowledge and skills about architectural design methods that are focused on people and society, sensitive to natural and built environment in the field of architecture.
5) Gaining skills to understand the relationship between architecture and other disciplines, to be able to cooperate, to develop comprehensive projects; to take responsibility in independent studies and group work.
6) Giving importance to the protection of natural and cultural values in the design of the built environment by being aware of the responsibilities in terms of human rights and social interests.
7) Giving importance to sustainability in the solution of design problems and the use of natural and artificial resources by considering the social, cultural and environmental issues of architecture.
8) Being able to convey and communicate all kinds of conceptual and practical thoughts related to the field of architecture by using written, verbal and visual media and information technologies.
9) Gaining the ability to understand and use technical information about building technology such as structural systems, building materials, building service systems, construction systems, life safety.
10) Being aware of legal and ethical responsibilities in design and application processes.