MBG4065 Introduction to Stem CellsBahçeşehir UniversityDegree Programs ARTIFICIAL INTELLIGENCE ENGINEERINGGeneral Information For StudentsDiploma SupplementErasmus Policy StatementNational QualificationsBologna Commission
ARTIFICIAL INTELLIGENCE ENGINEERING
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
MBG4065 Introduction to Stem Cells Spring
3 0 3 6
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction: English
Type of course: Non-Departmental Elective
Course Level: Bachelor’s Degree (First Cycle)
Mode of Delivery: Face to face
Course Coordinator : Dr. Öğr. Üyesi ELIZABETH HEMOND
Course Objectives: In this course, student should learn about the basic biology of embryonic, adult and cancer stem cells, molecular mechanisms of self renewal, differentiation and plasticity, reproductive and therapeutic cloning, epigenetic changes associated with stem cells, use of stem cells in cell based therapies and its ethical considerations.

Learning Outcomes

The students who have succeeded in this course;
1. Have a general understanding on stem cell biology.
2. Learn the basic features of stem cells and discuss the related mechanisms beneath.
3. Understand the effects of stem cells on the epigenetic changes.
4. Discuss stem cell based therapies and the related ethical issues stem from the uses of those therapies.
5. Categorize the stem cells.

Course Content

Basic biology of embryonic, adult and cancer stem cells. Molecular mechanisms of self renewal, differentiation and plasticity. Reproductive and therapeutic cloning. Epigenetic changes associated with stem cells. Use of stem cells in cell based therapies and its ethical considerations.

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Introduction and classification of stem cells
2) Basic biology of stem cells (self-renewal, pluripotency, plasticity, asymmetric division, niche)
3) Embryonic Stem Cells
4) Epiblast Stem Cells
5) Induced Pluripotent Stem Cells
6) Germline Stem Cells, Epigenetic Reprogramming I
7) Germline Stem Cells, Epigenetic Reprogramming II
8) Cancer Stem Cells
9) Mesenchymal Stem Cells
10) Hematopoeitic stem cells
11) Organ Specific Stem Cells (Neural- Vascular Endothelial, Pancreatic)
12) Organ Specific Stem Cells (Hepatic, Cardiac)
13) Organ Specific Stem Cells (Epidermal, Lung)
14) Review

Sources

Course Notes / Textbooks: Weekly course notes will be provided
References: Stem Cells Handbook, Steward Sell Publisher, 2003,ISBN 13: 9781588291134

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Attendance 10 % 5
Homework Assignments 1 % 15
Midterms 1 % 30
Final 1 % 50
Total % 100
PERCENTAGE OF SEMESTER WORK % 50
PERCENTAGE OF FINAL WORK % 50
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 3 42
Study Hours Out of Class 14 8 112
Midterms 1 2 2
Final 1 2 2
Total Workload 158

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) Have sufficient background in mathematics, science and artificial intelligence engineering.
2) Use theoretical and applied knowledge in the fields of mathematics, science and artificial intelligence engineering together for engineering solutions.
3) Identify, define, formulate and solve engineering problems, select and apply appropriate analytical methods and modeling techniques for this purpose.
4) Analyse a system, system component or process and design it under realistic constraints to meet desired requirements; apply modern design methods in this direction.
5) Select and use modern techniques and tools necessary for engineering applications.
6) Design and conduct experiments, collect data, and analyse and interpret results.
7) Work effectively both as an individual and as a multi-disciplinary team member.
8) Access information via conducting literature research, using databases and other resources
9) Follow the developments in science and technology and constantly update themself with an awareness of the necessity of lifelong learning.
10) Use information and communication technologies together with computer software with at least the European Computer License Advanced Level required by their field.
11) Communicate effectively, both verbal and written; know a foreign language at least at the European Language Portfolio B1 General Level.
12) Have an awareness of the universal and social impacts of engineering solutions and applications; know about entrepreneurship and innovation; and have an awareness of the problems of the age.
13) Have a sense of professional and ethical responsibility.
14) Have an awareness of project management, workplace practices, employee health, environment and work safety; know the legal consequences of engineering practices.