INTERNATIONAL TRADE AND BUSINESS
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Course Introduction and Application Information

Course Code	Course Name	Semester	Theoretical	Practical	Credit	ECTS
MBG4065	Introduction to Stem Cells	Fall	3	0	3	6

This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction:	English
Type of course:	Non-Departmental Elective
Course Level:	Bachelor’s Degree (First Cycle)
Mode of Delivery:	Face to face
Course Coordinator :	Dr. Öğr. Üyesi ELIZABETH HEMOND
Course Objectives:	In this course, student should learn about the basic biology of embryonic, adult and cancer stem cells, molecular mechanisms of self renewal, differentiation and plasticity, reproductive and therapeutic cloning, epigenetic changes associated with stem cells, use of stem cells in cell based therapies and its ethical considerations.

Learning Outcomes

The students who have succeeded in this course;
1. Have a general understanding on stem cell biology.
2. Learn the basic features of stem cells and discuss the related mechanisms beneath.
3. Understand the effects of stem cells on the epigenetic changes.
4. Discuss stem cell based therapies and the related ethical issues stem from the uses of those therapies.
5. Categorize the stem cells.

Course Content

Basic biology of embryonic, adult and cancer stem cells. Molecular mechanisms of self renewal, differentiation and plasticity. Reproductive and therapeutic cloning. Epigenetic changes associated with stem cells. Use of stem cells in cell based therapies and its ethical considerations.

Weekly Detailed Course Contents

Week	Subject	Related Preparation
1)	Introduction and classification of stem cells
2)	Basic biology of stem cells (self-renewal, pluripotency, plasticity, asymmetric division, niche)
3)	Embryonic Stem Cells
4)	Epiblast Stem Cells
5)	Induced Pluripotent Stem Cells
6)	Germline Stem Cells, Epigenetic Reprogramming I
7)	Germline Stem Cells, Epigenetic Reprogramming II
8)	Cancer Stem Cells
9)	Mesenchymal Stem Cells
10)	Hematopoeitic stem cells
11)	Organ Specific Stem Cells (Neural- Vascular Endothelial, Pancreatic)
12)	Organ Specific Stem Cells (Hepatic, Cardiac)
13)	Organ Specific Stem Cells (Epidermal, Lung)
14)	Review

Sources

Course Notes / Textbooks:	Weekly course notes will be provided
References:	Stem Cells Handbook, Steward Sell Publisher, 2003,ISBN 13: 9781588291134

Evaluation System

Semester Requirements	Number of Activities	Level of Contribution
Attendance	10	% 5
Homework Assignments	1	% 15
Midterms	1	% 30
Final	1	% 50
Total		% 100
PERCENTAGE OF SEMESTER WORK		% 50
PERCENTAGE OF FINAL WORK		% 50
Total		% 100

ECTS / Workload Table

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	3	42
Study Hours Out of Class	14	8	112
Midterms	1	2	2
Final	1	2	2
Total Workload			158

Contribution of Learning Outcomes to Programme Outcomes

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Has theoretical and practical knowledge on management, business, trade, economy, entrepreneurship, innovation, sustainable development related to International Trade and Business and can use this information
2)	Can collect data from different sources in the global business world and successfully apply research techniques, use information and communication technologies.
3)	Can analyze opportunities and threats with strategic thinking skills by using different resources and channels in the ever-changing global business world.
4)	Can communicate orally and in writing with a good knowledge of English grammar.
5)	He / she can transfer the knowledge and skills he / she has acquired in the field to the relevant people in written and oral form and evaluate them critically.
6)	Adopts the principles of business ethics with the awareness of professional responsibility and can apply these principles within the framework of legal rules in the field of global trade and business.
7)	He / she can collaborate in and out of the field, take responsibility, respect cultural differences and have ethical values.
8)	Has sufficient awareness of social rights, justice, cultural values, environmental awareness, occupational health and safety.
9)	With the lifelong learning skill acquired, she/he can identify learning needs and improve herself/himself