SOFTWARE ENGINEERING
Bachelor	TR-NQF-HE: Level 6	QF-EHEA: First Cycle	EQF-LLL: Level 6

Course Introduction and Application Information

Course Code	Course Name	Semester	Theoretical	Practical	Credit	ECTS
BME3005	Biostatistics	Spring	2	2	3	6

This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction:	English
Type of course:	Non-Departmental Elective
Course Level:	Bachelor’s Degree (First Cycle)
Mode of Delivery:	Face to face
Course Coordinator :	Dr. Öğr. Üyesi BURCU TUNÇ ÇAMLIBEL
Course Lecturer(s):	Dr. Öğr. Üyesi BURCU TUNÇ ÇAMLIBEL
Recommended Optional Program Components:	None
Course Objectives:	- The course provides an introduction to selected important topics in biostatistical concepts and reasoning. This course represents an introduction to the field and provides a survey of data and data types. Specific topics include tools for describing central tendency and variability in data; methods for performing inference on population means and proportions via sample data; statistical hypothesis testing and its application to group comparisons; issues of power and sample size in study designs; and random sample and other study types; regression analysis, confidence intervals, correlations

Learning Outcomes

The students who have succeeded in this course;
- The students who have succeeded in this course;
I. Interpret statistical results correctly, effectively, and in context.
II. Select an appropriate test for comparing two or more populations, and interpret and explain a p-value
III. Understand the concept of the power of data.
IV. Calculate and interpret confidence intervals for population means and proportions
V. Understand regression analysis and correlation of variables.

Course Content

Design of Experiments, Statistical programming: , Exploratory Data Analysis and Descriptive Statistics, Probability Theory, Sampling Distributions and the Central Limit Theorem, Estimation, Statistical Inference, Contingency tables, Nonparametric Tests, Power and sample size, ANOVA, Correlation and Regression, Logistic regression, Survival Analysis, applications on biological datasets.

Weekly Detailed Course Contents

Week	Subject	Related Preparation
1)	Introduction to biostatistics
2)	Descriptive Statistics
3)	Probability Theory
4)	Sampling Distributions and the Central Limit Theorem
5)	ANOVA
6)	The Special Case of Two Groups: the t test
7)	Contingency tables, Chi Square Test, z-test
8)	Fisher Exact Test, Relative Risk, Odds Ratio
9)	Power and Sample size
10)	Paired t-test, Repeated Measures of Analysis of Variance, McNemar's Test
11)	Nonparametric Tests: Mann-Whitney Rank-Sum Test, Wilcoxon Signed-Rank Test
12)	Nonparametric Tests: Kruskal-Wallis Test, Friedman Test
13)	Confidence Intervals
14)	Correlation and Regression

Sources

Course Notes / Textbooks:	Primer of Biostatistics, Stanton A. Glantz, McGraw-Hill, 7th Edition Fundamental of Biostatistics, Bernard Rosner, Cengage Learning, 8th Edition
References:

Evaluation System

Semester Requirements	Number of Activities	Level of Contribution
Quizzes	5	% 30
Midterms	1	% 30
Final	1	% 40
Total		% 100
PERCENTAGE OF SEMESTER WORK		% 60
PERCENTAGE OF FINAL WORK		% 40
Total		% 100

ECTS / Workload Table

Activities	Number of Activities	Duration (Hours)	Workload
Course Hours	14	3	42
Study Hours Out of Class	14	7	98
Quizzes	5	1	5
Midterms	1	3	3
Final	1	3	3
Total Workload			151

Contribution of Learning Outcomes to Programme Outcomes

No Effect	1 Lowest	2 Low	3 Average	4 High	5 Highest

	Program Outcomes	Level of Contribution
1)	Be able to specify functional and non-functional attributes of software projects, processes and products.
2)	Be able to design software architecture, components, interfaces and subcomponents of a system for complex engineering problems.
3)	Be able to develop a complex software system with in terms of code development, verification, testing and debugging.
4)	Be able to verify software by testing its program behavior through expected results for a complex engineering problem.
5)	Be able to maintain a complex software system due to working environment changes, new user demands and software errors that occur during operation.
6)	Be able to monitor and control changes in the complex software system, to integrate the software with other systems, and to plan and manage new releases systematically.
7)	Be able to identify, evaluate, measure, manage and apply complex software system life cycle processes in software development by working within and interdisciplinary teams.
8)	Be able to use various tools and methods to collect software requirements, design, develop, test and maintain software under realistic constraints and conditions in complex engineering problems.
9)	Be able to define basic quality metrics, apply software life cycle processes, measure software quality, identify quality model characteristics, apply standards and be able to use them to analyze, design, develop, verify and test complex software system.
10)	Be able to gain technical information about other disciplines such as sustainable development that have common boundaries with software engineering such as mathematics, science, computer engineering, industrial engineering, systems engineering, economics, management and be able to create innovative ideas in entrepreneurship activities.
11)	Be able to grasp software engineering culture and concept of ethics and have the basic information of applying them in the software engineering and learn and successfully apply necessary technical skills through professional life.
12)	Be able to write active reports using foreign languages and Turkish, understand written reports, prepare design and production reports, make effective presentations, give clear and understandable instructions.
13)	Be able to have knowledge about the effects of engineering applications on health, environment and security in universal and societal dimensions and the problems of engineering in the era and the legal consequences of engineering solutions.