|
Week |
Subject |
Related Preparation |
| 1) |
Functional groups and IUPAC names of organic compounds with the inclusion of all aliphatic and aromatic hydrocarbons.
Problem session to overview of organic chemistry
|
Review of topics |
| 2) |
Carbohydrates; Monosaccharides, Chiral Carbon Atoms, Enantiomers, Cyclic structures of monosaccharides, Mutarotation, Cyclic structures of Galactose, Cyclic structures of Fructose, Oxidation of monosaccharides, Disaccharides, Glycosides, Maltose, Lactose, Sucrose, Fermentation,
Determination of research bases of the student projects
|
Review of topics |
| 3) |
Polysaccharides, Amylose, Amylopectin, Glycogen, Cellulose, Lipids, Fatty acids,
Physical properties of Fatty acids, Waxes, fats and oils, Melting points of fats and oils.
Introduction to Experimental Project studies in laboratory.
|
Review of topics |
| 4) |
Amino acid structure, Amino acids with nonpolar side chains, Amino acids with uncharged polar side chains, Amino acids with charged polar side chains, Peptide Bonds, Classification and Characteristics.
Biochemistry laboratory
|
Review of topics |
| 5) |
Asid - base properties, Nomenclature, Optical activity Amino acids; Operational Classification, The Fischer Convention, The Cahn-Ingold-Prelog System, Chirality, Nonstandard amino acids.
Biochemistry laboratory
|
Review of topics |
| 6) |
Review
Research Project submission |
Review of topics |
| 7) |
Nucleotides and nucleic acids, The chemical structures of DNA and RNA.
Biochemistry laboratory
|
Review of topics |
| 8) |
DNA as the carrier of genetic information, Transforming principle, The Hereditary Molecule of many bacteriophages, Double helical DNA, The Watson-Crick structure B-DNA, DNA is semiconservatively replicated, Denaturation and renaturation.
Biochemistry laboratory.
|
Review of topics |
| 9) |
The size of DNA, Gene expression and replication, RNA Synthesis: Transcription, Protein synthesis: Translation, DNA Replication, Molecular cloning.
Biochemistry laboratory
|
Review of topics |
| 10) |
Chemical synthesis polypeptides, Covalent structures of Proteins: Primary structure, Three dimensional structures of Proteins, Secondary structure.
Biochemistry laboratory
|
Review of topics |
| 11) |
Fibrous proteins, Globular proteins: Tertiary structure, Quarternary structure, Enzymes, Substrate specificity, Coenzymes, regulation of enzymatic activity, Enzymes classification according to reaction type.
Biochemistry laboratory
|
Review of topics |
| 12) |
Bioenergetics, Metabolism and ATP Energy, Digestion of foods .
Biochemistry laboratory
|
Review of topics |
| 13) |
Important coenzymes in metabolic pathways: Redox reactions, Glycolysis: Oxidation of glucose, Reactions in Glycolysis.
Biochemistry laboratory-make up
|
Review of topics |
| 14) |
Citric acid cycle (TCA cycle), Electron transport chain, Chemiosmotic model: Oxidative phosporylation.
Other pathways of carbohydrate metabolism: The Glyoxylate cycle.
Experimental Project submission
|
Review of topics |
| Course Notes: |
1) Harper's Illustrated Biochemistry, Robert K. Murray, Darryl K. Granner, Peter A. Mayes, Victor W. Rodwell.
2) Chemistry, An introduction to General, Organic & Biological Chemistry, K.C. Timberlake, 7th Ed.,1999. |
| References: |
1) Biochemistry, D. Voet, J. G. Voet, 3rd Ed., John Wiley & Sons, USA., 2004.
2) Biochemistry: the Molecular Basis of Life, T. McKee and J. R. McKee. 3rd Ed. WCB/McGraw-Hill Press, Boston, MA 2003.
3) Principles of Biochemistry, D. L. Nelson & M. M. Cox, , 4th Ed., Worth Publishers, USA., 2005
4) Biochemistry, G. L. Zubay, 4th Ed., Mc Graw Hill, USA., 1998. |