ELECTRICAL AND ELECTRONICS ENGINEERING
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
EEE5572 Machine Learning for Bioinformatics II Fall
Spring
3 0 3 12
The course opens with the approval of the Department at the beginning of each semester

Basic information

Language of instruction: En
Type of course: Departmental Elective
Course Level: Bachelor
Mode of Delivery: Face to face
Course Coordinator : Dr. Öğr. Üyesi ZAFER İŞCAN
Course Objectives: This course surveys fundamental concepts in machine learning along with current applications in bioinformatics.

Learning Outputs

The students who have succeeded in this course;
1. Understand fundamental concepts in machine learning
2. Understand supervised learning and classification methods
3. Understand how machine learning concepts are applied to various bioinformatics problems
4. Describe essential bioinformatics applications and tools
5. Learn a machine learning software

Course Content

1. Neural networks
2. Vector machines
3. Hidden Markov models
4. Dynamic Bayesian networks
5. Protein structure and function prediction
6. Mass spectrometry
7. Gene networks

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Neural networks, multi-layer perceptrons, parameterization, learning rules
2) Neural networks (cont'd), learning algorithms, regression, classification
3) Neural networks (cont'd), applications in bioinformatics
4) Vector machines, basis function approach, radial basis function neural network, bio-basis function neural network
5) Vector machines (cont'd), support vector machines, relevance vector machines
6) Vector machines (cont'd), applications in bioinformatics
7) Hidden Markov models, learning, decoding
8) Dynamic Bayesian networks
9) Applications of hidden Markov models and dynamic Bayesian networks in bioinformatics
10) Gene networks, discrete Bayesian networks, inference with discrete Bayesian networks, learning a discrete Bayesian network
11) Gene networks (cont'd), causal networks, graphs, applications in bioinformatics, gene regulatory networks
12) Protein structure and function prediction
13) Mass spectrometry
14) Project presentations

Sources

Course Notes: 1. Machine Learning Approaches to Bioinformatics, Zheng Rong Yang, World Scientific Publishing Company, 2011.
References: 1. Data Mining for Bioinformatics, Sumeet Dua, CRC Press, 2013. 2. Bioinformatics: The Machine Learning Approach, Pierre Baldi and Soren Brunak, 2nd edition, MIT Press, 2001. 3. Pattern Recognition and Machine Learning, Christopher M. Bishop, 2nd printing edition, Springer, 2011. 4. Pattern Recognition, Sergios Theodoridis, Konstantinos Koutroumbas, Academic Press, 4th edition, 2008. 5. Introduction to Pattern Recognition: A Matlab Approach, Sergios Theodoridis, Aggelos Pikrakis, Konstantinos Koutroumbas, Dionisis Cavouras, Academic Press, 2010. 6. Pattern Classification, Richard O. Duda, Peter E. Hart, David G. Stork, 2nd edition, Wiley-Interscience, 2000.

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Attendance 14 % 15
Laboratory % 0
Application % 0
Field Work % 0
Special Course Internship (Work Placement) % 0
Quizzes % 0
Homework Assignments % 0
Presentation % 0
Project 1 % 30
Seminar % 0
Midterms 1 % 15
Preliminary Jury % 0
Final 1 % 40
Paper Submission % 0
Jury % 0
Bütünleme % 0
Total % 100
PERCENTAGE OF SEMESTER WORK % 30
PERCENTAGE OF FINAL WORK % 70
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 3 42
Laboratory 0 0 0
Application 0 0 0
Special Course Internship (Work Placement) 0 0 0
Field Work 0 0 0
Study Hours Out of Class 16 2 32
Presentations / Seminar 0 0 0
Project 8 10 80
Homework Assignments 5 6 30
Quizzes 0 0 0
Preliminary Jury 0
Midterms 1 3 3
Paper Submission 0
Jury 0
Final 1 3 3
Total Workload 190

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) Adequate knowledge in mathematics, science and electric-electronic engineering subjects; ability to use theoretical and applied information in these areas to model and solve engineering problems.
2) Ability to identify, formulate, and solve complex engineering problems; ability to select and apply proper analysis and modeling methods for this purpose.
3) Ability to design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the desired result; ability to apply modern design methods for this purpose. (Realistic constraints and conditions may include factors such as economic and environmental issues, sustainability, manufacturability, ethics, health, safety issues, and social and political issues, according to the nature of the design.)
4) Ability to devise, select, and use modern techniques and tools needed for electrical-electronic engineering practice; ability to employ information technologies effectively.
5) Ability to design and conduct experiments, gather data, analyze and interpret results for investigating engineering problems.
6) Ability to work efficiently in intra-disciplinary and multi-disciplinary teams; ability to work individually.
7) Ability to communicate effectively in English and Turkish (if he/she is a Turkish citizen), both orally and in writing.
8) Recognition of the need for lifelong learning; ability to access information, to follow developments in science and technology, and to continue to educate him/herself.
9) Awareness of professional and ethical responsibility.
10) Information about business life practices such as project management, risk management, and change management; awareness of entrepreneurship, innovation, and sustainable development.
11) Knowledge about contemporary issues and the global and societal effects of engineering practices on health, environment, and safety; awareness of the legal consequences of engineering solutions.