MATHEMATICS (TURKISH, PHD)
PhD TR-NQF-HE: Level 8 QF-EHEA: Third Cycle EQF-LLL: Level 8

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
GEN2001 Cell Biology Fall 3 2 4 6
The course opens with the approval of the Department at the beginning of each semester

Basic information

Language of instruction: En
Type of course: Departmental Elective
Course Level:
Mode of Delivery: Face to face
Course Coordinator : Dr. Öğr. Üyesi EMİNE KANDEMİŞ
Course Objectives: The main objective of the course is to understand cell as the `fundamental unit of life` and therefore cell biology forms the base upon which all modern biology and medicine is built on. The course will emphasize the study of eukaryotic cell structure and function, including membrane transport, cellular communication, flow of genetic information, cell division and immune responses. Experimental techniques used in understanding cell biology will be discussed throughout the course.

Learning Outputs

The students who have succeeded in this course;
1. Introduction to course, define types of prokaryotic and eukaryotic cells, their structural, evolutionary and genomic features
2. Describe molecular components of the cell
3. Discuss how cells read the genome: from DNA to protein, control of gene expression
4. Define and compare methods on how to manipulate proteins, DNA, RNA and visualize the cell
5. Define membrane structure, membrane transport of small molecules
6. Identify the intracellular compartments and how proteins are sorted
7. Discuss signaling mechanisms in the cell
8. Define cell cycle and apoptosis mechanisms
9. Identify cell junctions, adhesion, and extracellular matrix
10. Discuss mechanisms of fertilization, differentiation, organogenesis
11. Discuss cancer
12. Define adaptive immune system

Course Content

This is an introductory course in cellular sciences. Its content includes studies of cells, including their physiological properties, structure, the organelles they contain, their interactions with their environment, life cycle, division and death.

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Introduction to the Cell Reading
2) Cell Chemistry and Biosynthesis Reading
3) Basic Genetic Mechanisms Reading
4) Methods Used in Cell Biology Reading
5) Internal Organization of The Cell Reading
6) Intracellular Compartments, Protein and Lipid Sorting Reading
7) Cell Communication Reading
8) Overview Reading
9) Cytoskeleton Reading
10) Cell Cycle and Programmed Cell Death Reading
11) Cells in Their Social Context and Development of Multicellular Organisms Reading
12) Histology: The Lives and Deaths of Cells in Tissues Reading
13) Cancer Reading
14) Adaptive Immune System Reading

Sources

Course Notes: MBG2005 Cell Biology I Course Notes
References: 1. Molecular Biology of the Cell, Bruce Alberts, Alexander Johnson, Julian Lewis, Martin Raff, Keith Roberts, Peter Walter, Fifth Edition, Garland Science, 2007 (ISBN-13: 978-0815341055) 2. Molecular Cell Biology, Harvey Lodish, Arnold Berk, Chris A. Kaiser, Monty Krieger, Matthew P. Scott, Anthony Bretscher, Hidde Ploegh, Paul Matsudaira, Sixth Edition, W. H. Freeman, 2008 (ISBN-13: 978-0716776017) 3. Lehninger Principles of Biochemistry, David L. Nelson, Michael M. Cox, Fifth Edition, Freeman, 2008 (ISBN-13: 978-0716771081)

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Attendance 14 % 5
Laboratory 11 % 20
Application % 0
Field Work % 0
Special Course Internship (Work Placement) % 0
Quizzes % 0
Homework Assignments % 0
Presentation % 0
Project % 0
Seminar % 0
Midterms 1 % 25
Preliminary Jury % 0
Final 1 % 50
Paper Submission % 0
Jury % 0
Bütünleme % 0
Total % 100
PERCENTAGE OF SEMESTER WORK % 50
PERCENTAGE OF FINAL WORK % 50
Total % 100

ECTS / Workload Table

Activities Number of Activities Workload
Course Hours 14 42
Laboratory 11 22
Application
Special Course Internship (Work Placement)
Field Work
Study Hours Out of Class 14 98
Presentations / Seminar
Project
Homework Assignments
Quizzes
Preliminary Jury
Midterms 1 2
Paper Submission
Jury
Final 1 2
Total Workload 166

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution