| NURSING (ENGLISH) | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
| Course Code | Course Name | Semester | Theoretical | Practical | Credit | ECTS |
| NUR1007 | Biochemistry | Fall | 2 | 0 | 2 | 3 |
| The course opens with the approval of the Department at the beginning of each semester |
| Language of instruction: | En |
| Type of course: | Must Course |
| Course Level: | Bachelor |
| Mode of Delivery: | Face to face |
| Course Coordinator : | Dr. Öğr. Üyesi EVİN KORKMAZ |
| Course Objectives: | This course is designed to provide the groundwork for many scientific study fields. Course topics include organic structures and metabolism in human body and basic principles and applications both in biochemistry and clinical biochemistry. |
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The students who have succeeded in this course; 1) will have basic knowledge in the field of nursery biochemistry, 2) will be able to learn basic topics in biochemistry, 3) will be able to research, understand and evaluate scientific literature, 4) will be able to perceive and interpret metabolic events during digestion of macromolecules 5) will be able to determine biomolecules and their monomeric structural units 6) will have knowledge to examine the metabolism and functions of macronutrients and micronutrients 7) will be able to develop the ability to use the general information about the functions and metabolism of hormones 8) will learn to classification of the vitamins and will be able to determine their monomeric structure. 9) will be able to explain the specifity of vitamins and minerals as biochemical catalysts in enzymatic reactions. 10) will be able to learn th eimportance of clinical biochemistry in nursing; will have knowledge about respiratory and metabolic acidosis/alkalosis, biological fluids for the routine biochemistry analysis in clinical biochemistry, routine blood collection (phlebotomy), blood composition and preanalytical errors. |
| Carbohydrates, lipids, amino acids, nucleic acids, gene expression and replication, RNA synthesis, protein synthesis, DNA replication, molecular cloning, chemical synthesis of polypeptides, covalent structures of proteins, enzymes, bioenergetics, metabolism and ATP energy, digestion of nutrients, carbohydrate metabolism. |
| Week | Subject | Related Preparation | |
| 1) | Introduction to biochemistry and clinical biochemistry, Bioenergetics and Oxidative Phosphorylation, Adenosine triphosphate as an energy carrier, Electron transport chain, Carbohydrates: Structure and classification; monosaccharides, disaccharides, polysaccharides Digestion and absorption of carbohydrates | ||
| 2) | Carbohydrate metabolism: Glycolysis, citric acid (TCA) cycle , Other metabolic pathways of carbohydrate metabolism, Ethyl alcohol metabolism, Disorders of carbohydrate metabolism | ||
| 3) | Lipids: Classification, Digestion and absorbtion of lipids, lipoprotein (Chylomicron, VLDL, LDL, HDL) metabolism, Disorders of lipoprotein metabolism | ||
| 4) | Lipid metabolism, Lipogenesis, Beta-oxidation of fatty acids, Ketone bodies, Cholesterol metabolism | ||
| 5) | Proteins: Structure and classification of proteins, Hemoglobin, Digestion and absorption of proteins | ||
| 6) | Protein metabolism, Disorders of protein metabolism, Integration and regulation of metabolism, Fed and fasting state | ||
| 7) | Nucleotides and nucleic acids, the chemical structure of DNA and RNA, DNA as the genetic information carrier, The double helix structure of DNA, The semiconservative replication of DNA, RNA synthesis: Transcription, Protein synthesis: The chemical synthesis of polypeptides: Translation | ||
| 8) | Enzymes, Substrate specifity, Coenzymes, The regulation of enzymatic activity, Classification of enzymes due to the reactions they catalyse, Importance of isoenzymes in function test panels in clinical biochemistry in the diagnosis of diseases | ||
| 9) | Midterm Exam -1 | ||
| 10) | Hormones: Types of hormones, principles of general actions of hormones, the hypothalamo-pituitary regulatory system (hypothalamus and pituitary hormones), Hypothalamo-pituitarythyroid axis, (thyroid hormones, parathyroid gland hormones), Hypothalamo-pituitary-adrenal axis (corticotropin-releasing hormone, adrenocorticotropic hormone, cortisol), Hypothalamo-pituitarygonadal axis, (gonadotropinreleasing hormone, testosterone, FSH, LH, progesterone, estradiol), Growth hormone axis (Growth hormone-releasing hormone and somatostatin, growth hormone, insulin-like growth factor I), The prolactin axis (dopamine, prolactin), Pancreas hormones (insülin, glucagon) | ||
| 11) | Vitamins: The chemical structures, metabolism, functions, sources and symptoms of inadequacy of water soluble vitamins (Vitamin C, Folic acid , Vitamin B12, tiamin, riboflavin, pyridoxin, niacin, pantotenic acid….) and lipid soluble vitamins (Vitamin A, Vitamin E, Vitamin K and Vitamin D; Vitamin D and Ca metabolism) | ||
| 12) | Minerals: Macro elements (Calcium, Phosphorus, Magnesium, Sulphur), Micro (trace) elements (Iron, Zinc, Fluoride, Copper) and Ultra trace elements (Iodine, Selenium, Manganese, Chromium, Molybdenum, Cobalt, Fluoride) | ||
| 13) | Electrolytes, water metabolism, acid-base balance, respiratory and metabolic acidosis/alkalosis and buffering systems in our body (Bicarbonate/carbonic acid, Protein, Hemoglobin and Phosphate buffer systems) | ||
| 14) | Midterm exam-2 | ||
| Course Notes: | |
| References: | 1.Pratt, C. W. (2018). Essential biochemistry. Wiley. 2.Miskevich, F. (2017). Biochemistry 2. BarCharts, Inc. 3.Appling, D. R. (2016). Biochemistry : concepts and connections. Pearson Education Limited. 4.Rodwell, V. W. (2015). Harper’s illustrated biochemistry. McGraw-Hill. |
| Semester Requirements | Number of Activities | Level of Contribution |
| Attendance | % 0 | |
| Laboratory | % 0 | |
| Application | % 0 | |
| Field Work | % 0 | |
| Special Course Internship (Work Placement) | % 0 | |
| Quizzes | % 0 | |
| Homework Assignments | % 0 | |
| Presentation | % 0 | |
| Project | % 0 | |
| Seminar | % 0 | |
| Midterms | 2 | % 50 |
| Preliminary Jury | % 0 | |
| Final | 1 | % 50 |
| Paper Submission | % 0 | |
| Jury | % 0 | |
| Bütünleme | % 0 | |
| Total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 50 | |
| PERCENTAGE OF FINAL WORK | % 50 | |
| Total | % 100 | |
| Activities | Number of Activities | Duration (Hours) | Workload |
| Course Hours | 14 | 3 | 42 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Special Course Internship (Work Placement) | 0 | 0 | 0 |
| Field Work | 0 | 0 | 0 |
| Study Hours Out of Class | 14 | 1 | 14 |
| Presentations / Seminar | 0 | 0 | 0 |
| Project | 0 | 0 | 0 |
| Homework Assignments | 0 | 0 | 0 |
| Quizzes | 0 | 0 | 0 |
| Preliminary Jury | 0 | 0 | 0 |
| Midterms | 2 | 6 | 12 |
| Paper Submission | 0 | 0 | 0 |
| Jury | 0 | 0 | 0 |
| Final | 1 | 10 | 10 |
| Total Workload | 78 | ||
| No Effect | 1 Lowest | 2 Low | 3 Average | 4 High | 5 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | "To plan and assess nursing care within a holistic approach, in accordance with theoretical and evidence-based practices. " | 3 |
| 2) | To act in accordance with ethical principles and values in Nursing practices. | |
| 3) | To use life-long learning, problem-solving and critical thinking skills. | |
| 4) | To use Nursing models/theories in health promotion, protection and care. | |
| 5) | To take part in research, projects and activities within sense of social responsibility and interdisciplinary approach. | |
| 6) | "To have skills for training and consulting according to health education needs of individual, family and the community. " | |
| 7) | "To be sensitive to health problems of the community and and to able to offer solutions. " | |
| 8) | "To be able to use interpersonal and intercultural communication skills effectively in Nursing pratices. " | |
| 9) | "To be able to use healthcare/information technologies in Nursing practice and research. " | |
| 10) | To be able to search for literature in health sciences databases and information sources to access to information and use the information effectively. | |
| 11) | To be able to monitor occupational information using at least one foreign language, to collaborate and communicate with colleagues at international level. | |
| 12) | To take responsibility and lead in events in order to contribute to health services and Nursing profession. | 3 |