| DENTAL MEDICINE | |||||
| Bachelor | TR-NQF-HE: Level 6 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
| Course Code | Course Name | Semester | Theoretical | Practical | Credit | ECTS |
| DENT1004 | Medical Biology and Genetics | Fall | 2 | 0 | 4 | 4 |
| The course opens with the approval of the Department at the beginning of each semester |
| Language of instruction: | En |
| Type of course: | Must Course |
| Course Level: | Bachelor |
| Mode of Delivery: | Hybrid |
| Course Coordinator : | Dr. Öğr. Üyesi FATMA ÖNER |
| Course Objectives: | This course aims to improve dentistry student's knowledge about medical biology and genetics in medical context. Fundamentals of human genetics and genomics as applied to health and disease will be thought to improve the students' diagnostic and research skills. |
|
The students who have succeeded in this course; By the end of the course, you will be able to; • Explain the evolutionary basis of genome • Explain the common and different characteristics of species • Explain the organization of human genome • Define genetic disorders and medical genetics. • Explain the types of genetic disorders • Explain the content and structure DNA • Explain the mitochondrial genome structure and properties • List and classify steps of cell cycle. • Explain the steps and different features of mitosis and meiosis. • Explain the medical relevance of mitosis and meiosis. • Explain phenotype and genotype with their correlations. • Describe the central dogma of biology • Explains the basic principles of transcription and translation • Define polymorphisms and its importance in medical genetics. • List the common variation types in human genome with respect to their size, frequency and basis for the polymorphisms • Explain the mutation rates for selected human diseases • Explain the sex differences and age effects on mutation rates • List the different types of mutations, their consequences and frequencies • Explain the term dynamic mutations |
| Medical Biology is a discipline that uses molecular biology, cell biology and molecular genetics fields to understand and explain underlying cause of medical situations. Thus, the molecular and genetic mechanisms of a healthy cell is studied in order to understand the causes of a diseased state. |
| Week | Subject | Related Preparation | |
| 1) | Introduction to Medical Genetics, Online Introduction to Genome | ||
| 2) | Gene Structure and Function, Online DNA Replication | ||
| 3) | Transcription | ||
| 4) | Translation | ||
| 5) | Recombination, Cell Division | ||
| 6) | Genomics and Proteomics, Proteomics | ||
| 7) | Metabolomics | ||
| 8) | Human Genetics | ||
| 9) | Mendelian and Non-Mendelian Inheritance in Humans, Patterns of Single Gene Inheritance | ||
| 10) | Complex Inheritance of Common Multifactorial Diseases | ||
| 11) | Chromosome Biology, Chromosome Biology and Disorders | ||
| 12) | Stem Cell Biology | ||
| 13) | Cancer Biology | ||
| 14) | Mutations and Population Genetics | ||
| 15) | Evolution | ||
| 16) | Medical Biology and Biotechnology | ||
| Course Notes: | Alberst, 6th Edition, Molecular Biology of the Cell. Garland Science |
| References: |
| Semester Requirements | Number of Activities | Level of Contribution |
| Attendance | % 0 | |
| Laboratory | % 0 | |
| Application | % 0 | |
| Field Work | % 0 | |
| Special Course Internship (Work Placement) | % 0 | |
| Quizzes | 8 | % 20 |
| Homework Assignments | % 0 | |
| Presentation | % 0 | |
| Project | % 0 | |
| Seminar | % 0 | |
| Midterms | 4 | % 40 |
| Preliminary Jury | % 0 | |
| Final | 1 | % 40 |
| Paper Submission | % 0 | |
| Jury | % 0 | |
| Bütünleme | % 0 | |
| Total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 60 | |
| PERCENTAGE OF FINAL WORK | % 40 | |
| Total | % 100 | |
| No Effect | 1 Lowest | 2 Low | 3 Average | 4 High | 5 Highest |
| Program Outcomes | Level of Contribution |