| BIOENGINEERING (ENGLISH, THESIS) | |||||
| Master | TR-NQF-HE: Level 7 | QF-EHEA: Second Cycle | EQF-LLL: Level 7 | ||
| Course Code | Course Name | Semester | Theoretical | Practical | Credit | ECTS |
| BNG5115 | Cell and Tissue Engineering | Fall Spring |
3 | 0 | 3 | 12 |
| The course opens with the approval of the Department at the beginning of each semester |
| Language of instruction: | En |
| Type of course: | Departmental Elective |
| Course Level: | |
| Mode of Delivery: | Face to face |
| Course Coordinator : | Prof. Dr. GÜLAY BULUT |
| Course Objectives: | Tissue Engineering is an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function or a whole. This introductory course aims to address the most important and fundamental topics - biological as well as engineering - of contemporary tissue engineering research. |
|
The students who have succeeded in this course; 1. Provide students with a foundation for engineering tissues based on Nature's own design and optimization criteria. 2. Stimulate the students' ability to critically review recent published work in the field 3. Provide students with the necessary background and vocabulary to communicate with biomedical experts and clinicians. |
| Tissue Engineering is an interdisciplinary field that applies the principles of engineering and life sciences toward the development of biological substitutes that restore, maintain, or improve tissue function or a whole. This introductory course aims to address the most important and fundamental topics - biological as well as engineering - of contemporary tissue engineering research. |
| Week | Subject | Related Preparation | |
| 1) | Tissue Engineering | ||
| 2) | Surface immobilization of adhesion ligands for investigations of cell-substrate interactions | ||
| 3) | Biomaterials: Protein-surface interactions | ||
| 4) | Engineering biomaterials for tissue engineering: The 10–100 micron size scale | ||
| 5) | Regeneration templates | ||
| 6) | Fluid shear stress effects on cellular function | ||
| 7) | The biology of stem cells | ||
| 8) | Cell motility and tissue architecture | ||
| 9) | Midterm | ||
| 10) | The importance of stromal cells | ||
| 11) | Tissue engineering of bone and skeletal muscle | ||
| 12) | Tissue engineering of the liver & cartilage | ||
| 13) | Tissue engineering in the nervous system | ||
| 14) | Final | ||
| Course Notes: | 1. Animal Cell Culture: Essential Methods, Wiley, John M. Davis, 2011, ISBN10: 9780470666586 2. Tissue Engineering, CRC Press, Bernhard Palsson, Jeffrey A. Hubbell, Robert Plonsey, Joseph D. Bronzino, 2003, ISBN10: 9780849318122 3. Stem Cell Engineering: Principles and Practices, CRC Press, David Schaffer, Joseph D. Bronzino, Donald R. Peterson, 2012, ISBN10: 9781439872048 4. Tissue Engineering: Principles and Practices, CRC Press, John P. Fisher, Antonios G. Mikos, Joseph D.Bronzino, Donald R. Peterson, 2012, ISBN10: 9781439874004 |
| References: | Lecture notes. |
| Semester Requirements | Number of Activities | Level of Contribution |
| Attendance | 1 | % 10 |
| Laboratory | 0 | % 0 |
| Application | 0 | % 0 |
| Field Work | 0 | % 0 |
| Special Course Internship (Work Placement) | 0 | % 0 |
| Quizzes | 0 | % 0 |
| Homework Assignments | 0 | % 0 |
| Presentation | 0 | % 0 |
| Project | 0 | % 0 |
| Seminar | 0 | % 0 |
| Midterms | 1 | % 30 |
| Preliminary Jury | 0 | % 0 |
| Final | 1 | % 60 |
| Paper Submission | 0 | % 0 |
| Jury | 0 | % 0 |
| Bütünleme | % 0 | |
| Total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 40 | |
| PERCENTAGE OF FINAL WORK | % 60 | |
| Total | % 100 | |
| Activities | Number of Activities | Duration (Hours) | Workload |
| Course Hours | 14 | 4 | 56 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Special Course Internship (Work Placement) | 0 | 0 | 0 |
| Field Work | 0 | 0 | 0 |
| Study Hours Out of Class | 14 | 7 | 98 |
| Presentations / Seminar | 0 | 0 | 0 |
| Project | 0 | 0 | 0 |
| Homework Assignments | 0 | 0 | 0 |
| Quizzes | 0 | 0 | 0 |
| Preliminary Jury | 0 | 0 | 0 |
| Midterms | 1 | 20 | 20 |
| Paper Submission | 0 | 0 | 0 |
| Jury | 0 | 0 | 0 |
| Final | 1 | 30 | 30 |
| Total Workload | 204 | ||
| No Effect | 1 Lowest | 2 Low | 3 Average | 4 High | 5 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | An understanding of the advanced concepts of Mathematics (calculus, analysis, linear algebra, differential equations, statistics), Natural Sciences (physics, chemistry, biology), and Engineering Sciences (electronics, material science, mechanics, thermal and fluid systems, control, signal and image processing, microcontrollers) relevant to Biomedical Engineering. | |
| 2) | An ability to use at an advanced level the techniques, skills, and modern engineering tools (including software) necessary for engineering practice. | |
| 3) | The capability of designing and conducting advanced experiments and of analyzing and evaluating data. | |
| 4) | An ability to design the components of complex systems and processes under realistic constraints. | |
| 5) | Acquisition of the skills needed to develop products (device, system, process) which are used in diagnosis, prevention, treatment and cure of diseases. | |
| 6) | An ability to communicate knowledge and opinion efectively, both oral and in writing. | |
| 7) | An ability to assume initiative and individual resposibility, and to cooperate with team-mates from other disciplines. | |
| 8) | A kowledge of the current needs and problems of society, and an awareness of the social and global impact of engineering solutions. | |
| 9) | Assimilation of the ethics and responsibilities of the profession. | |
| 10) | Recognition of the importance of life-long learning, and participation therein. |