| BIOENGINEERING (ENGLISH, THESIS) | |||||
| Master | TR-NQF-HE: Level 7 | QF-EHEA: Second Cycle | EQF-LLL: Level 7 | ||
| Course Code | Course Name | Semester | Theoretical | Practical | Credit | ECTS |
| BNG5113 | Cellular and Molecular Bioengineering | Fall | 3 | 0 | 3 | 8 |
| The course opens with the approval of the Department at the beginning of each semester |
| Language of instruction: | En |
| Type of course: | Must Course |
| Course Level: | |
| Mode of Delivery: | Face to face |
| Course Coordinator : | Prof. Dr. GÜLAY BULUT |
| Course Objectives: | The molecular and cellular bases of life from an engineering perspective. Analysis and engineering of biomolecular structure and dynamics, enzyme function, molecular interactions, metabolic pathways, signal transduction, and cellular mechanics. |
|
The students who have succeeded in this course; 1) Discuss molecular and cellular bases of life through bioengineering perspective. 2) Learn biomolecular structure and dynamics. 3) Learn enzyme function and dynamics. 4) Discuss metabolic pathways and signal transduction. |
| This course investigates the molecules and mechanisms underlying cellular function from an engineering perspective, utilizing physical, chemical and quantitative approaches. |
| Week | Subject | Related Preparation | |
| 1) | DNA replication | ||
| 2) | DNA elasticity | ||
| 3) | DNA sequencing technologies I | ||
| 4) | DNA sequencing technologies II | ||
| 5) | Melting and other structural transitions in DNA | ||
| 6) | DNA nanotechnology | ||
| 7) | Driving forces in protein folding and binding I | ||
| 8) | Driving forces in protein folding and binding II | ||
| 9) | Allostery | ||
| 10) | Protein design I | ||
| 11) | Protein design II | ||
| 12) | Metabolic engineering | ||
| 13) | Synthetic biology I | ||
| 14) | Synthetic biology II | ||
| Course Notes: | Griffiths, J. B., 1990. Animal Cell Biotechnology, Vol 1-4; Eds. R. E. Spier, Acad. Pres Inc. Freshney I. R. 1994. Culture of Animal Cells. Wiley Liss Inc. Neumann, K., H., A.Kumar, J. Imani, 2009. Plant Cell and Tissue Culture – A Tool in Biotechnology; Basics and Application. Springer – Verlag , Berlin Heidelberg. George, E. F., M.A. Hall, G.-J.De Klerk, 2008. Plant Propagation by Tissue Culture. 3rd Edition Volume 1. Springer Publishing Company. Loyola-Vargas, V.M., F. Vázquez-Flota, 2006. Plant Cell Culture Protocols, Second Edition, Humana Press Inc. Bailey, J. E., D. F. Ollis, 1986. Biochemical Engineering Fundamentals, McGraw Hill. |
| References: | Related articles. İlgili makaleler. |
| Semester Requirements | Number of Activities | Level of Contribution |
| Attendance | 1 | % 10 |
| Laboratory | 0 | % 0 |
| Application | 0 | % 0 |
| Field Work | 0 | % 0 |
| Special Course Internship (Work Placement) | 0 | % 0 |
| Quizzes | 0 | % 0 |
| Homework Assignments | 0 | % 0 |
| Presentation | 0 | % 0 |
| Project | 0 | % 0 |
| Seminar | 0 | % 0 |
| Midterms | 1 | % 30 |
| Preliminary Jury | 0 | % 0 |
| Final | 1 | % 60 |
| Paper Submission | 0 | % 0 |
| Jury | 0 | % 0 |
| Bütünleme | % 0 | |
| Total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 40 | |
| PERCENTAGE OF FINAL WORK | % 60 | |
| Total | % 100 | |
| Activities | Number of Activities | Duration (Hours) | Workload |
| Course Hours | 14 | 4 | 56 |
| Laboratory | 0 | 0 | 0 |
| Application | 0 | 0 | 0 |
| Special Course Internship (Work Placement) | 0 | 0 | 0 |
| Field Work | 0 | 0 | 0 |
| Study Hours Out of Class | 14 | 7 | 98 |
| Presentations / Seminar | 0 | 0 | 0 |
| Project | 0 | 0 | 0 |
| Homework Assignments | 0 | 0 | 0 |
| Quizzes | 0 | 0 | 0 |
| Preliminary Jury | 0 | 0 | 0 |
| Midterms | 1 | 20 | 20 |
| Paper Submission | 0 | 0 | 0 |
| Jury | 0 | 0 | 0 |
| Final | 1 | 30 | 30 |
| Total Workload | 204 | ||
| No Effect | 1 Lowest | 2 Low | 3 Average | 4 High | 5 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | An understanding of the advanced concepts of Mathematics (calculus, analysis, linear algebra, differential equations, statistics), Natural Sciences (physics, chemistry, biology), and Engineering Sciences (electronics, material science, mechanics, thermal and fluid systems, control, signal and image processing, microcontrollers) relevant to Biomedical Engineering. | 5 |
| 2) | An ability to use at an advanced level the techniques, skills, and modern engineering tools (including software) necessary for engineering practice. | 5 |
| 3) | The capability of designing and conducting advanced experiments and of analyzing and evaluating data. | 5 |
| 4) | An ability to design the components of complex systems and processes under realistic constraints. | 4 |
| 5) | Acquisition of the skills needed to develop products (device, system, process) which are used in diagnosis, prevention, treatment and cure of diseases. | 4 |
| 6) | An ability to communicate knowledge and opinion efectively, both oral and in writing. | 5 |
| 7) | An ability to assume initiative and individual resposibility, and to cooperate with team-mates from other disciplines. | 3 |
| 8) | A kowledge of the current needs and problems of society, and an awareness of the social and global impact of engineering solutions. | 3 |
| 9) | Assimilation of the ethics and responsibilities of the profession. | 4 |
| 10) | Recognition of the importance of life-long learning, and participation therein. | 4 |