MATHEMATICS (TURKISH, PHD)
PhD TR-NQF-HE: Level 8 QF-EHEA: Third Cycle EQF-LLL: Level 8

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
BME4103 Immunology Fall 2 2 3 6
The course opens with the approval of the Department at the beginning of each semester

Basic information

Language of instruction: En
Type of course: Departmental Elective
Course Level:
Mode of Delivery: Face to face
Course Coordinator : Dr. Öğr. Üyesi HAKAN SOLMAZ
Course Objectives: This course is designed to teach the processes through which the living host maintains constancy in its internal environment when confronted with an interaction/ invasion/ attack by foreign substances.

Learning Outputs

The students who have succeeded in this course;
ON COMPLETION OF THIS SECTION THE STUDENT SHOULD BE ABLE TO:

- Appreciate three functions of the immune system
- Distinguish between innate immunity and acquired immunity
- Discuss how the clonal selective theory explains the immune systems's
- Ability to recognize millions of antigens
- Describe the basic structural and functional components of the immune system

Course Content

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Introduction to immunology and terminology
2) Immunogenetics: Major Histocompatibility Complex, Clam I and II Antigens, Blood Groups.
3) Antigens: Exogenous vs. Endogenous Antigens, Physical & Chemical Properties, Adjuvants
4) Antibody: History, Families & Subclames, Function, Structure: 1° vs. 3D structures.
5) Complement: Pathways, Proteins, Membrane Attack Complex, Regulatory Mechanism, Deficiencies.
6) Immunophysiology: Cellular Interaction in Antibody Formation, Primary vs. 2° responses, Memory, Specific Immune Response, Functional Cells, Surface Markers.
7) Functional Cells: Lymphocytes, Macrophagen, Natural Killer Cells, Helper Cells, B Cells, Models & Regulation of Antibody Formation.
8) Antigen-Antibody Interactions: Primary Manifestation, Secondary Manifestation, Measurement: Radioimmunoassay, Precipitin & Agglutination Reaction, Coombs Reaction, Complement Fixation.
9) Mechanism & Tissue Injury, Inflammation, Acute-Chronic Phases.
10) Mechanisms of Tissue Injury: Immunologic Reactions, Ancyphylaxis, Antigen-Antibody Complexes, Serum Sickness, Delayed Hypersensitivity.
11) Mechanism of Immunity to Parasitic Disease and Fungal
12) Mechanism of Immunity to Bacterial Disease: Non-specific, Specific.
13) Mechanism of Immunity to Viral Diseases
14) Immune Defenses in Tumor Immunity

Sources

Course Notes: Joseph A Bellanti, Immunology III , WB Saunders Co. Philadelphia, 1985
References:

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Attendance 10 % 0
Laboratory 0 % 0
Application 0 % 0
Field Work 0 % 0
Special Course Internship (Work Placement) 0 % 0
Quizzes 1 % 10
Homework Assignments 0 % 0
Presentation 0 % 0
Project 0 % 0
Seminar 0 % 0
Midterms 1 % 30
Preliminary Jury 0 % 0
Final 1 % 60
Paper Submission 0 % 0
Jury 0 % 0
Bütünleme % 0
Total % 100
PERCENTAGE OF SEMESTER WORK % 40
PERCENTAGE OF FINAL WORK % 60
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 3 42
Laboratory 0 0 0
Application 0 0 0
Special Course Internship (Work Placement) 0 0 0
Field Work 0 0 0
Study Hours Out of Class 14 6 84
Presentations / Seminar 1 3 3
Project 0 0 0
Homework Assignments 0 0 0
Quizzes 1 3 3
Preliminary Jury 0 0 0
Midterms 1 3 3
Paper Submission 0 0 0
Jury 0 0 0
Final 1 3 3
Total Workload 138

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution