Wave motion, electromagnetic theory, electromagnetic spectrum, propagation of light , measurement of optical properties of tissues, optics, microscopy, lasers, mechanisms of laser-tissue ineractions, lasers in surgery, tissue welding, laser tweezers, lasers in imaging, diagnostic applications, electrosurgery versus laser surgery, laser safety.
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Week |
Subject |
Related Preparation |
1) |
Introduction, wave motion; plane, spherical and cylindrical waves, Electromagnetic theory, electromagnetic waves, energy and momentum of radiation. Dipole emission, emission and absorption by atoms and molecules, black body radiation, electromagnetic spectrum.
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2) |
Propagation of light: reflection, refraction, scattering, interference and diffraction. Measurement of optical properties of tissue, Geometrical optics, fiberoptics. Microscopy and limits of resolution, mechanisms of contrast.
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3) |
Eye and vision, perception of color. Spontaneous and stimulated emission, principle of laser, cavity modes, lasing media, pumping mechanisms, continuous and pulsed regimes.
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4) |
"Mechanisms of laser-tissue interactions I: Photochemical. Photodynamic therapy,
photostimulation, cytotoxicity of UV light."
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5) |
Mechanisms of laser-tissue interactions II: Photothermal. Heat generation, heat conduction and distribution. Thermal damage to tissue. Laser-Induced Interstitial Thermotherapy (LIIT).
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6) |
Mechanisms of laser-tissue interactions III: Photomechanical. Explosive evaporation, shock and acoustic waves, cavitation, jet formation.
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7) |
Mechanisms of laser-tissue interactions IV: Dielectric breakdown, plasma-mediated ablation.
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8) |
Lasers in Ophthalmology.
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9) |
Lasers in Dermatology.
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10) |
Lasers in General Surgery, Cardiovascular Surgery, Gynecology. Tissue welding. Low power lasers. Micromanipulation and cell surgery.
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11) |
Lasers in Imaging.
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12) |
Diagnostic applications: Autofluorescence, Raman spectroscopy, Scattering Light Spectroscopy, Doppler velocimetry.
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13) |
"Electrosurgery: Mechanisms of interaction and tissue damage. Pros and cons vs.
laser surgery."
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14) |
Laser safety: lasers classification.
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Program Outcomes |
Level of Contribution |
1) |
Build up a body of knowledge in mathematics, science and engineering subjects; use theoretical and applied information in these areas to model and solve engineering problems. |
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2) |
identify, formulate, and solve complex engineering problems; select and apply proper analysis and modeling methods for this purpose. |
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3) |
Design a complex system, process, device or product under realistic constraints and conditions, in such a way as to meet the desired result; apply modern design methods for this purpose. (Realistic constraints and conditions may include factors such as economic and environmental issues, sustainability, manufacturability, ethics, health, safety issues, and social and political issues, according to the nature of the design.) |
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4) |
Devise, select, and use modern techniques and tools needed for engineering management practice; employ information technologies effectively. |
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5) |
Design and conduct experiments, collect data, analyze and interpret results for investigating engineering management problems. |
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6) |
Cooperate efficiently in intra-disciplinary and multi-disciplinary teams; and show self-reliance when working independently. |
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7) |
Demonstrate effective communication skills in both oral and written English and Turkish. |
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8) |
Recognize the need for lifelong learning; show ability to access information, to follow developments in science and technology, and to continuously educate him/herself. |
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9) |
Develop an awareness of professional and ethical responsibility. |
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10) |
Know business life practices such as project management, risk management, and change management; develop an awareness of entrepreneurship, innovation, and sustainable development. |
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11) |
Know contemporary issues and the global and societal effects of engineering practices on health, environment, and safety; recognize the legal consequences of engineering solutions. |
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12) |
Develop effective and efficient managerial skills. |
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