NEUROSCIENCE (ENGLISH, THESIS)
Master TR-NQF-HE: Level 7 QF-EHEA: Second Cycle EQF-LLL: Level 7

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
NSC5021 Neuropharmacology Spring 3 0 3 7
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction: Turkish
Type of course: Departmental Elective
Course Level:
Mode of Delivery: Face to face
Course Coordinator : Assoc. Prof. NERİMAN İPEK SÖNMEZ
Course Lecturer(s): Prof. Dr. DEMET AKIN
Course Objectives: This course covers the pharmacology of the nervous system with particular emphasis on the mechanisms of action of different drugs that affect synaptic transmission. It is aimed to introduce the basic features of synaptic transmission and drug-sensitive areas in synaptic transmission. This course aimed to gain the clinical use of different therapeutic drug groups and to teach components of integrative chemical communication in central nervous system.

Learning Outcomes

The students who have succeeded in this course;
1) Identify the major excitatory and inhibitory CNS neurotransmitters in the CNS.
2) Identify the sites of drug action at synapses and the mechanisms by which drugs modulate synaptic transmission.
3) Describe the probable mechanisms of action and the major characteristics of autonomic nervous system associated drugs, including receptor interactions, adverse effects (from chronic use and in overdose), drug interactions, and clinical uses.
4) Describe the probable mechanisms of action and the major characteristics of sedative hypnotics and antidepressants, including receptor interactions, adverse effects (from chronic use and in overdose), drug interactions, and clinical uses.
5) Describe the probable mechanisms of action and the major characteristics of antipsychotic agents, including receptor interactions, adverse effects (from chronic use and in overdose), drug interactions, and clinical uses.
6) Identify the most important drugs used in the management of essential tremor, Huntington’s disease, drug-induced dyskinesias, restless legs syndrome, and Wilson’s disease
7)Identify an opioid receptor antagonist and a mixed agonist-antagonist.
8) Identify general general anesthetics and local anesthetics.
9) Identify the mechanisms of antiseizure drug action at the levels of specific ion channels or neurotransmitter systems.

Course Content

This course includes;

Introduction to CNS pharmacology, Introduction to autonomic nervous system, Parasympathomimetics & parasympatholytics, Sympathomimetics & sympatholytics, Neuromuscular blocking agents, Sedative Hypnotics, Antipsychotics and effective agents in the treatment of bipolar disorder, Antidepressants, General anesthetics & Local anesthetics - antiepileptics and Parkinson's treatment indicated agents

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Introduction to CNS Pharmacology Course Presentations and Recommended Books
2) Introduction the Autonomic Nervous System Course Presentations and Recommended Books
3) Parasympathomimetic and Parasympatholytic drugs Course Presentations and Recommended Books
4) Sympathomimetic and sympatholytic drugs Course Presentations and Recommended Books
5) Neuromuscular Blocking Agents Course Presentations and Recommended Books
6) Sedative Hypnotics Course Presentations and Recommended Books
7) Antipsychotics and drug that are used Bipolar Disorder Course Presentations and Recommended Books
8) Antidepressants Course Presentations and Recommended Books
9) General Anesthetics and Local Anesthetics Course Presentations and Recommended Books
10) Antiseizure and antiparkinson drugs Course Presentations and Recommended Books
11) Students presentations -
12) Student Presentations -
13) Students Presentations -
14) Students Presentations -

Sources

Course Notes / Textbooks: Ders notları "itslearning" sistemine yüklenecektir./ Lecture notes will be uploaded to "itslearning".
References: 1.Kayaalp, SO: Rasyonel Tedavi Yönünden Tıbbi Farmakoloji, Ankara. 2002.
2.Goodman and Gilman Farmakoloji ve Tedavi El Kitabı, Güneş Tıp Kitabevi, 2017.
3.Katzung & Trevor: Basic and Clinical Pharmacology 16th Edition. McGraw Hill Medical Books, 2023.

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Presentation 1 % 40
Final 1 % 60
Total % 100
PERCENTAGE OF SEMESTER WORK % 40
PERCENTAGE OF FINAL WORK % 60
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 3 42
Study Hours Out of Class 14 10 140
Presentations / Seminar 1 1 1
Final 1 2 2
Total Workload 185

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) Understands fundamental theoretical and practical knowledge in the field of neuroscience. 4
2) Gains advanced knowledge of the structure, functioning, and disorders of the nervous system. 4
3) Can design and analyze experiments using scientific research methods. 4
4) Communicates effectively and contributes to teamwork in multidisciplinary environments. 2
5) Conducts scientific research in accordance with ethical standards and reports results responsibly. 3
6) Follows current literature in neuroscience and makes critical evaluations. 4
7) Applies appropriate statistical methods to analyze neuroscientific data. 3
8) Develops original work in the field using new knowledge and technologies. 3
9) Evaluates the importance of neuroscience for individual and public health. 4
10) Effectively presents knowledge and skills through written, oral, and visual means. 3