GASTRONOMY (TURKISH)
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
MBG4066 Cancer Genetics and Biology Spring 3 0 3 6
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction: English
Type of course: Non-Departmental Elective
Course Level: Bachelor’s Degree (First Cycle)
Mode of Delivery: Face to face
Course Coordinator : Dr. Öğr. Üyesi ELIZABETH HEMOND
Course Objectives: In this course, student should learn about genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Learning Outcomes

The students who have succeeded in this course;
1. Have a general knowledge on genetic changes induced by cancer.
2. Discuss terms of oncogene and tumor suppressor gene.
3. Understand hereditary cancers and DNA repair cancer relationship.
4. Discuss cell cycle, apoptosis and multicellular cell interactions in cancer.

Course Content

Genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Cancer as a disease
2) Model organisms and techniques used in cancer studies
3) Mutated genomes of cancer cells, DNA gains, DNA losses and nucleotide changes
4) Epigenetic changes in cancer cells
5) Viral and cellular oncogenes
6) Tumor suppressor genes
7) Overview of phenotypic changes in cancer cells
8) Cell cycle and cancer
9) DNA damage response in cancer cells
10) DNA repair and cancer
11) Senescence aberrations in cancer cells
12) Apoptotic and autophagic aberrations in cancer cells
13) Invasive and metastatic abilities of cancer cells
14) Tumor heterogeneity and "cancer stem cells"

Sources

Course Notes / Textbooks: The Molecular Basis of Cancer.2nd edition Author(s): Mendelsohn, Howley, Israel & Liotta. Publisher: W. B. Saunders Company, Philadelphia, 2011
References: The Genetic Basis of Human Cancer Author(s): B. Vogelstein & K. W. Kinzler Publisher: McGraw-Hill, New York, 1999

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Attendance 10 % 5
Homework Assignments 1 % 15
Midterms 1 % 30
Final 1 % 50
Total % 100
PERCENTAGE OF SEMESTER WORK % 50
PERCENTAGE OF FINAL WORK % 50
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 3 42
Study Hours Out of Class 14 8 112
Midterms 1 2 2
Final 1 2 2
Total Workload 158

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) - Possess advanced level theoretical and practical knowledge supported by textbooks with updated information, practice equipments and other resources.
2) Use of advanced theoretical and practical knowledge within the field. -Interpret and evaluate data, define and analyze problems, develop solutions based on research and proofs by using acquired advanced knowledge and skills within the field.
3) Inform people and institutions, transfer ideas and solution proposals to problems in written and orally on issues in the field. - Share the ideas and solution proposals to problems on issues in the field with professionals and non-professionals by the support of qualitative and quantitative data. -Organize and implement project and activities for social environment with a sense of social responsibility. -Monitor the developments in the field and communicate with peers by using a foreign language at least at a level of European Language Portfolio B1 General Level. -Use informatics and communication technologies with at least a minimum level of European Computer Driving License Advanced Level software knowledge.
4) Evaluate the knowledge and skills acquired at an advanced level in the field with a critical approach. -Determine learning needs and direct the learning. -Develop positive attitude towards lifelong learning.
5) Act in accordance with social, scientific, cultural and ethic values on the stages of gathering, implementation and release of the results of data related to the field. - Possess sufficient consciousness about the issues of universality of social rights, social justice, quality, cultural values and also, environmental protection, worker's health and security.
6) Conduct studies at an advanced level in the field independently. - Take responsibility both as a team member and individually in order to solve unexpected complex problems faced within the implementations in the field. - Planning and managing activities towards the development of subordinates in the framework of a project