MBG4066 Cancer Genetics and BiologyBahçeşehir UniversityDegree Programs SOCIOLOGYGeneral Information For StudentsDiploma SupplementErasmus Policy StatementNational QualificationsBologna Commission
SOCIOLOGY
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
MBG4066 Cancer Genetics and Biology Fall 3 0 3 6
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction: English
Type of course: Non-Departmental Elective
Course Level: Bachelor’s Degree (First Cycle)
Mode of Delivery: Face to face
Course Coordinator : Dr. Öğr. Üyesi ELIZABETH HEMOND
Course Objectives: In this course, student should learn about genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Learning Outcomes

The students who have succeeded in this course;
1. Have a general knowledge on genetic changes induced by cancer.
2. Discuss terms of oncogene and tumor suppressor gene.
3. Understand hereditary cancers and DNA repair cancer relationship.
4. Discuss cell cycle, apoptosis and multicellular cell interactions in cancer.

Course Content

Genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Cancer as a disease
2) Model organisms and techniques used in cancer studies
3) Mutated genomes of cancer cells, DNA gains, DNA losses and nucleotide changes
4) Epigenetic changes in cancer cells
5) Viral and cellular oncogenes
6) Tumor suppressor genes
7) Overview of phenotypic changes in cancer cells
8) Cell cycle and cancer
9) DNA damage response in cancer cells
10) DNA repair and cancer
11) Senescence aberrations in cancer cells
12) Apoptotic and autophagic aberrations in cancer cells
13) Invasive and metastatic abilities of cancer cells
14) Tumor heterogeneity and "cancer stem cells"

Sources

Course Notes / Textbooks: The Molecular Basis of Cancer.2nd edition Author(s): Mendelsohn, Howley, Israel & Liotta. Publisher: W. B. Saunders Company, Philadelphia, 2011
References: The Genetic Basis of Human Cancer Author(s): B. Vogelstein & K. W. Kinzler Publisher: McGraw-Hill, New York, 1999

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Attendance 10 % 5
Homework Assignments 1 % 15
Midterms 1 % 30
Final 1 % 50
Total % 100
PERCENTAGE OF SEMESTER WORK % 50
PERCENTAGE OF FINAL WORK % 50
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 3 42
Study Hours Out of Class 14 8 112
Midterms 1 2 2
Final 1 2 2
Total Workload 158

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) To learn and compare major sociology perspectives, both classical and contemporary, and apply all of them to analysis of social conditions.
2) To be able to identify the basic methodological approaches in building sociological and anthropological knowledge at local and global levels
3) To be able to use theoretical and applied knowledge acquired in the fields of statistics in social sciences.
4) To have a basic knowledge of other disciplines (including psychology, history, political science, communication studies and literature) that can contribute to sociology and to be able to make use of this knowledge in analyzing sociological processes
5) To have a knowledge and practice of scientific and ethical principles in collecting, interpreting and publishing sociological data also develop ability how to share this data with experts and lay people, using effective communication skills
6) To develop competence in analyzing and publishing sociological knowledge by using computer software for quantitative and qualitative analysis; and develop an attitute for learning new techniques in these fields.
7) To identify and to have a knowledge of the theories related to urban and rural sociology and demography, and political sociology, sociology of gender, sociology of body, visual sociology, sociology of work, sociology of religion, sociology of knowledge and sociology of crime.
8) To have knowledge of how sociology is positioned as a scientific discipline from a philosophical and historical perspective
9) To have the awareness of social issues in Turkish society, to develop critical perspective in analysing these issues and to have a knowledge of the works of Turkish sociologists and to be able to transfer this knowledge
10) To have the awareness of social issues and global societal processes and to apply sociological analysis to development and social responsibility projects
11) To have the ability to define a research question, design a research project and complete a written report for various fields of sociology, either as an individual or as a team member.
12) To be able to transfer the knowledge gained in the areas of sociology to the level of secondary school.