EUROPEAN UNION RELATIONS
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
MBG4066 Cancer Genetics and Biology Spring 3 0 3 6
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction: English
Type of course: Non-Departmental Elective
Course Level: Bachelor’s Degree (First Cycle)
Mode of Delivery: Face to face
Course Coordinator : Dr. Öğr. Üyesi ELIZABETH HEMOND
Course Objectives: In this course, student should learn about genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Learning Outcomes

The students who have succeeded in this course;
1. Have a general knowledge on genetic changes induced by cancer.
2. Discuss terms of oncogene and tumor suppressor gene.
3. Understand hereditary cancers and DNA repair cancer relationship.
4. Discuss cell cycle, apoptosis and multicellular cell interactions in cancer.

Course Content

Genetic changes in cancer, phenotype of cancer cells, oncogenes, tumor suppressor genes, hereditary cancers, cell cycle, apoptosis, senescence, DNA repair and cancer, multicellular interactions in cancer.

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Cancer as a disease
2) Model organisms and techniques used in cancer studies
3) Mutated genomes of cancer cells, DNA gains, DNA losses and nucleotide changes
4) Epigenetic changes in cancer cells
5) Viral and cellular oncogenes
6) Tumor suppressor genes
7) Overview of phenotypic changes in cancer cells
8) Cell cycle and cancer
9) DNA damage response in cancer cells
10) DNA repair and cancer
11) Senescence aberrations in cancer cells
12) Apoptotic and autophagic aberrations in cancer cells
13) Invasive and metastatic abilities of cancer cells
14) Tumor heterogeneity and "cancer stem cells"

Sources

Course Notes / Textbooks: The Molecular Basis of Cancer.2nd edition Author(s): Mendelsohn, Howley, Israel & Liotta. Publisher: W. B. Saunders Company, Philadelphia, 2011
References: The Genetic Basis of Human Cancer Author(s): B. Vogelstein & K. W. Kinzler Publisher: McGraw-Hill, New York, 1999

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Attendance 10 % 5
Homework Assignments 1 % 15
Midterms 1 % 30
Final 1 % 50
Total % 100
PERCENTAGE OF SEMESTER WORK % 50
PERCENTAGE OF FINAL WORK % 50
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 3 42
Study Hours Out of Class 14 8 112
Midterms 1 2 2
Final 1 2 2
Total Workload 158

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) To be able to examine, interpret data and assess ideas with the scientific methods in the area of EU studies. 2
2) To be able to inform authorities and institutions in the area of EU studies, to be able to transfer ideas and proposals supported by quantitative and qualitative data about the problems. 2
3) To be introduced to and to get involved in other disciplines that EU studies are strongly related with (political science, international relations, law, economics, sociology, etc.) and to be able to conduct multi-disciplinary research and analysis on European politics. 3
4) To be able to evaluate current news on European Union and Turkey-EU relations and identify, analyze current issues relating to the EU’s politics and policies. 2
5) To be able to use English in written and oral communication in general and in the field of EU studies in particular. 1
6) To have ethical, social and scientific values throughout the processes of collecting, interpreting, disseminating and implementing data related to EU studies. 1
7) To be able to assess the historical development, functioning of the institutions and decision-making system and common policies of the European Union throughout its economic and political integration in a supranational framework. 2
8) To be able to evaluate the current legal, financial and institutional changes that the EU is going through. 2
9) To explain the dynamics of enlargement processes of the EU by identifying the main actors and institutions involved and compare previous enlargement processes and accession process of Turkey. 2
10) To be able to analyze the influence of the EU on political, social and economic system of Turkey. 2
11) To acquire insight in EU project culture and to build up project preparation skills in line with EU format and develop the ability to work in groups and cooperate with peers. 2
12) To be able to recognize theories and concepts used by the discipline of international relations and relate them to the historical development of the EU as a unique post-War political project. 3