| DENTAL MEDICINE | |||||
| Bachelor | TR-NQF-HE: Level 7 | QF-EHEA: First Cycle | EQF-LLL: Level 6 | ||
| Course Code | Course Name | Semester | Theoretical | Practical | Credit | ECTS |
| MBG4065 | Introduction to Stem Cells | Spring | 3 | 0 | 3 | 6 |
| This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester. |
| Language of instruction: | English |
| Type of course: | Non-Departmental Elective |
| Course Level: | Bachelor’s Degree (First Cycle) |
| Mode of Delivery: | Face to face |
| Course Coordinator : | Assist. Prof. ELİF EREN |
| Course Objectives: | In this course, student should learn about the basic biology of embryonic, adult and cancer stem cells, molecular mechanisms of self renewal, differentiation and plasticity, reproductive and therapeutic cloning, epigenetic changes associated with stem cells, use of stem cells in cell based therapies and its ethical considerations. |
|
The students who have succeeded in this course; 1. Have a general understanding on stem cell biology. 2. Learn the basic features of stem cells and discuss the related mechanisms beneath. 3. Understand the effects of stem cells on the epigenetic changes. 4. Discuss stem cell based therapies and the related ethical issues stem from the uses of those therapies. 5. Categorize the stem cells. |
| Basic biology of embryonic, adult and cancer stem cells. Molecular mechanisms of self renewal, differentiation and plasticity. Reproductive and therapeutic cloning. Epigenetic changes associated with stem cells. Use of stem cells in cell based therapies and its ethical considerations. The course will be based on lectures, readings and discussions. |
| Week | Subject | Related Preparation |
| 1) | Introduction to Stem Cells | |
| 2) | Adult vs Embryonic Stem Cells | |
| 3) | Stem Cell Pluripotency, Self- Renewal and Differentiation | |
| 4) | Genetic and Epigenetic Regulation of Stem Cells | |
| 5) | Induced Pluripotent Stem Cells I | |
| 6) | Induced Pluripotent Stem Cells II | |
| 7) | Stem Cell Research Ethics | |
| 8) | Cancer Stem Cells | |
| 9) | Mesenchymal Stem Cells | |
| 10) | Hematopoeitic Stem Cells | |
| 11) | Cardiac Stem Cells | |
| 12) | Skeletal Muscle Stem Cells | |
| 13) | Adipose Stem Cells | |
| 14) | Intestinal Stem Cells |
| Course Notes / Textbooks: | Weekly course notes will be provided |
| References: | Stem Cells Handbook, Steward Sell Publisher, 2003,ISBN 13: 9781588291134 |
| Semester Requirements | Number of Activities | Level of Contribution |
| Presentation | 1 | % 25 |
| Midterms | 1 | % 35 |
| Final | 1 | % 40 |
| Total | % 100 | |
| PERCENTAGE OF SEMESTER WORK | % 60 | |
| PERCENTAGE OF FINAL WORK | % 40 | |
| Total | % 100 | |
| Activities | Number of Activities | Duration (Hours) | Workload |
| Course Hours | 14 | 3 | 42 |
| Study Hours Out of Class | 14 | 8 | 112 |
| Midterms | 1 | 2 | 2 |
| Final | 1 | 2 | 2 |
| Total Workload | 158 | ||
| No Effect | 1 Lowest | 2 Low | 3 Average | 4 High | 5 Highest |
| Program Outcomes | Level of Contribution | |
| 1) | Follows national and international developments in clinical practice and behaves scientifically. | |
| 2) | Adopts professionalism and ethics in professional practices. | |
| 3) | Communicates effectively with colleagues, patients, patients' relatives, and in interdisciplinary settings. | |
| 4) | Prioritizes health in individual and community-based dental practices. | |
| 5) | Applies institutional leadership and management principles in professional practices. | |
| 6) | Monitors and implements information technologies in professional practices. | |
| 7) | Considers professional principles in diagnostic and treatment processes in clinical practices. | |
| 8) | Supports entrepreneurship for the advancement of the profession. | |
| 9) | Ensures continuous technological and professional development. |