MEDICINE
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
MED1001 Molecular Basis of Cell Fall 3 2 4 6

Basic information

Language of instruction: English
Type of course: Must Course
Course Level: Bachelor’s Degree (First Cycle)
Mode of Delivery: Face to face
Course Coordinator : Dr. Öğr. Üyesi YASEMİN ÇANILLIOĞLU
Course Lecturer(s): Assoc. Prof. YEŞİM NEĞİŞ
Prof. Dr. SERDAR DURDAĞI
Recommended Optional Program Components: None
Course Objectives: The aim of this course is to provide knowledge about the structural properties and basic functions of organic compounds and biomolecules; structure, function, and evaluation of the cell, bioenergetics, light, and lenses; terminology of anatomy, normal structure, and anatomy of the appendicular skeleton and vertebral column; radiologic anatomy of the upper and lower extremities and laboratory safety rules; get skills about hand washing and get skills about working as a part of a team.

Learning Outcomes

The students who have succeeded in this course;
1. Student knows the structure, synthesis and basic functions of organic compounds and biomolecules
2. Student defines the properties of acids, bases, pH, pK and buffer solutions.
3. Student defines the structural properties, evolution and organelles of the cell.
4. Student defines the structure and functions of DNA, RNA, proteins, lipids, carbohydrates, enzymes, vitamins and hormones
5. Student gains knowledge on basic concepts, descriptions and nomenculature in anatomy and morphology
6. Student gains knowledge on bone structure

Detailed information:
https://bau.edu.tr/blogs/tr/15244-tip-fakultesi-sinif-1-mezuniyet-oncesi-egitim

Course Content

Introduction to biomolecules, water, solubility, acid, base, buffer, structure and functions of amino acids, proteins and carbohydrates, polysaccharides, histological structures of connective, cartilage and bone tissue, osteogenesis, cell evolution, cell structure and functions, cell organelles, upper and lower extremities radiological anatomy, protein structure and properties, anatomy of appendicular skeleton and vertebral column, light and lenses.

Weekly Detailed Course Contents

Week Subject Related Preparation
1) The universal features of cells Basic concepts, descriptions and nomenculature (terminology), general information about bones Introduction to Biochemistry Introduction to Biomolecules Biochemical properties of water The Cell Structure & Function (Prokaryotic-Eukaryotic Cells) Ionization of water and pH The Structure and Properties of Amino Acids Microscopy Acids, Bases and Buffers Introduction to Histology Introduction to Embryology Basic Concepts of Molecular Biophysics: Energetics of Intra and Intermolecular Interactions Epithelium and Surface Differentiations Protein Structure and Function
2) Clinical Skills Lab Rules Acidic and Basic Properties of Amino Acids Cell-cell junctions and cell surface differentions Cell membrane; Lipid bilayer, membrane proteins and other molecules Histology of Lining and Glandular Epithelium Introduction to Biophysics:Biophysics as Interdisciplinary Field Introduction to physiology The Laws of Thermodynamics in Biological Systems Gibbs free energy and equilibrium coefficient Histology of Connective tissue Heat Capacities and the Boltzmann Distribution Light and lenses Scapula, Clavicula, Humerus, Radius, Ulna and Skeleton of the Hand Cytoskeleton Intermediate filaments Histology of Cartilage Hand Washing Techniques Coxal Bone and Femur Cytoskeleton; Actin and Microtubules Cytoskeleton; Motor Proteins
3) Biochemistry Lab: Introduction to Biochemistry laboratory equipments & instruments Anatomy Lab: Scapula, Clavicula, Humerus, Radius, Ulna and Skeleton of the Hand Histology Lab: Use of Microscope and Epithelial Tissue CSL: Hand Washing Techniques Histological Structure of Bone Tissue Tibia, Fibula, Patella, Skeleton of the Foot Structure and Function of Carbohydrates Homeostasis and control systems Vertebral Column, Sacral Bone, Coccygeal Bone, Sternum, Ribs Structure and Function of Osteogenesis Histology Lab: Connective Tissue Biophysic Lab: Measurement, Light and Lenses Histology Lab: Cartilage Tissue Biochemistry Lab: Preperation of Buffers and Determination of pH
4) Polysaccharides Organelle-2 Extracellular matrix and cell adhesion molecules Anatomy Lab: Vertebral Column, Sacral Bone, Coccygeal Bone, Sternum, Ribs (costae) Histology Lab: Bone Tissue & Osteogenesis Biophysic Lab: Measurement, Light and Lenses Histology Lab: Cartilage Tissue Histology Lab: Bone Tissue & Osteogenesis

Sources

Course Notes / Textbooks: ANATOMY;
1) Clinically Oriented Anatomy, Keith L. Moore, Anne M. R. Agur Arthur F. Dalley; Publisher: LWW; 7th edition
2) Gray's Clinical Photographic Dissector of the Human Body ; M Loukas, B Beninnger, RS Tubbs; Elsevier; 2013
3) Gray's Clinical Neuroanatomy: The Anatomic Basis for Clinical Neuroscience, 1e (Gray's Anatomy); Elliott L. Mancall, David G. Brock Publisher: Saunders; 1 edition
4) Sobotta Atlas of Human Anatomy, Package, 15th ed., English/Latin

HISTOLOGY AND EMBRYOLOGY;
1) Color Textbook of Histology. Leslie P. Gardner, James L. Hiatt, Third Edition, Saunders-Elsevier
2) The Developing Human, Clinically Oriented Embryology. Keith L. Moore, T.V.N. Persaud. 8th Edition. Elsevier, Saunders

PHYSIOLOGY;
1) Guyton&Hall;Medical Physiology
2) Ganong's Review of Medical Physiology

BIOPHYSICS;
1) Biophysics, Mehmet Can Kalyoncu, Istanbul, 2015, Istanbul Univ. Cerrahpasa Tip Fakultesi
2) Biyofizik, Ferit Pehlivan, 8. Baski, Pelikan Yayin Evi, Ankara, 2015

MEDICAL BIOLOGY;
1) Molecular Biology of the Cell, Alberts B. et al., 6th Edition, Garland Science

BIOCHEMISTRY;
1) Harpers Illustrated Biochemistry (Lange Medical Book) 29th Edition
2) Lehninger Principles of Biochemistry, 7th Edtition
References: ANATOMY;
1) Clinically Oriented Anatomy, Keith L. Moore, Anne M. R. Agur Arthur F. Dalley; Publisher: LWW; 7th edition
2) Gray's Clinical Photographic Dissector of the Human Body ; M Loukas, B Beninnger, RS Tubbs; Elsevier; 2013
3) Gray's Clinical Neuroanatomy: The Anatomic Basis for Clinical Neuroscience, 1e (Gray's Anatomy); Elliott L. Mancall, David G. Brock Publisher: Saunders; 1 edition
4) Sobotta Atlas of Human Anatomy, Package, 15th ed., English/Latin

HISTOLOGY AND EMBRYOLOGY;
1) Color Textbook of Histology. Leslie P. Gardner, James L. Hiatt, Third Edition, Saunders-Elsevier
2) The Developing Human, Clinically Oriented Embryology. Keith L. Moore, T.V.N. Persaud. 8th Edition. Elsevier, Saunders

PHYSIOLOGY;
1) Guyton&Hall;Medical Physiology
2) Ganong's Review of Medical Physiology
BIOPHYSICS;
1) Biophysics, Mehmet Can Kalyoncu, Istanbul, 2015, Istanbul Univ. Cerrahpasa Tip Fakultesi
2) Biyofizik, Ferit Pehlivan, 8. Baski, Pelikan Yayin Evi, Ankara, 2015

MEDICAL BIOLOGY;
1) Molecular Biology of the Cell, Alberts B. et al., 6th Edition, Garland Science

BIOCHEMISTRY;
1) Harpers Illustrated Biochemistry (Lange Medical Book) 29th Edition
2) Lehninger Principles of Biochemistry, 7th Edtition

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Midterms 1 % 60
Final 1 % 40
Total % 100
PERCENTAGE OF SEMESTER WORK % 60
PERCENTAGE OF FINAL WORK % 40
Total % 100

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) Integrates the knowledge, skills and attitudes acquired from basic and clinical medical sciences, behavioral sciences and social sciences, and uses them in health service delivery.
2) In patient management, shows a biopsychosocial approach that takes into account the socio-demographic and sociocultural background of the individual, regardless of language, religion, race and gender.
3) In the provision of health services, prioritizes the protection and development of the health of individuals and society.
4) Taking into account the individual, societal, social and environmental factors affecting health; does the necessary work to maintain and improve the state of health.
5) By recognizing the characteristics, needs and expectations of the target audience, provides health education to healthy/sick individuals and their relatives and other healthcare professionals.
6) Shows a safe, rational and effective approach in health service delivery, prevention, diagnosis, treatment, follow-up and rehabilitation processes.
7) Performs invasive and/or non-invasive procedures in diagnosis, treatment, follow-up and rehabilitation processes in a safe and effective way for the patient.
8) Provides health services by considering patient and employee health and safety.
9) In the provision of health services, takes into account the changes in the physical and socioeconomic environment on a regional and global scale, as well as the changes in the individual characteristics and behaviors of the people who apply to it.
10) Takes good medical practice into account while carrying out his/her profession.
11) Fulfills its duties and obligations within the framework of ethical principles, rights and legal responsibilities required by its profession.
12) Demonstrates decisive behavior in providing high-quality health care, taking into account the integrity of the patient.
13) Evaluates his/her performance in his/her professional practice by considering his/her emotions and cognitive characteristics.
14) Advocates improving the provision of health services by considering the concepts of social reliability and social responsibility for the protection and development of public health.
15) Can plan and carry out service delivery, training and consultancy processes related to individual and community health in cooperation with all components for the protection and development of health.
16) Evaluates the impact of health policies and practices on individual and community health indicators and advocates increasing the quality of health services.
17) The physician attaches importance to the protection of his/her own physical, mental and social health, and does what is necessary for this
18) Shows exemplary behavior and leads the healthcare team during service delivery.
19) Uses resources cost-effectively, for the benefit of society and in accordance with the legislation, in the planning, implementation and evaluation processes of health services in the health institution he/she is the manager of.
20) Establishes positive communication within the health team it serves and assumes different team roles when necessary.
21) Is aware of the duties and responsibilities of the health workers in the health team and acts accordingly.
22) In the professional practices, works in harmony and effectively with the colleagues and other professional groups.
23) Communicates effectively with patients, their relatives, healthcare professionals, other professional groups, institutions and organizations.
24) Communicates effectively with individuals and groups that require a special approach and have different socio-cultural characteristics.
25) In the diagnosis, treatment, follow-up and rehabilitation processes, shows a patient-centered approach that associates the patient with the decision-making mechanisms.
26) Plans and implements scientific research, when necessary, for the population it serves, and uses the results and/or the results of other research for the benefit of the society.
27) Reaches and critically evaluates current literature knowledge about his/her profession.
28) Applies the principles of evidence-based medicine in clinical decision making.
29) Uses information technologies to increase the effectiveness of its work on health care, research and education.
30) Effectively manages individual work processes and career development.
31) Demonstrates skills in acquiring and evaluating new knowledge, integrating it with existing knowledge, applying it to professional situations and adapting to changing conditions throughout professional life.
32) Selects the right learning resources to improve the quality of the health service it offers, organizes its own learning process