BIOMEDICAL ENGINEERING
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
BME4103 Immunology Spring 2 2 3 6
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction: English
Type of course: Departmental Elective
Course Level: Bachelor’s Degree (First Cycle)
Mode of Delivery: Face to face
Course Coordinator : Dr. Öğr. Üyesi HAKAN SOLMAZ
Recommended Optional Program Components: None
Course Objectives: This course is designed to teach the processes through which the living host maintains constancy in its internal environment when confronted with an interaction/ invasion/ attack by foreign substances.

Learning Outcomes

The students who have succeeded in this course;
ON COMPLETION OF THIS SECTION THE STUDENT SHOULD BE ABLE TO:

- Appreciate three functions of the immune system
- Distinguish between innate immunity and acquired immunity
- Discuss how the clonal selective theory explains the immune systems's
- Ability to recognize millions of antigens
- Describe the basic structural and functional components of the immune system

Course Content

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Introduction to immunology and terminology
2) Immunogenetics: Major Histocompatibility Complex, Clam I and II Antigens, Blood Groups.
3) Antigens: Exogenous vs. Endogenous Antigens, Physical & Chemical Properties, Adjuvants
4) Antibody: History, Families & Subclames, Function, Structure: 1° vs. 3D structures.
5) Complement: Pathways, Proteins, Membrane Attack Complex, Regulatory Mechanism, Deficiencies.
6) Immunophysiology: Cellular Interaction in Antibody Formation, Primary vs. 2° responses, Memory, Specific Immune Response, Functional Cells, Surface Markers.
7) Functional Cells: Lymphocytes, Macrophagen, Natural Killer Cells, Helper Cells, B Cells, Models & Regulation of Antibody Formation.
8) Antigen-Antibody Interactions: Primary Manifestation, Secondary Manifestation, Measurement: Radioimmunoassay, Precipitin & Agglutination Reaction, Coombs Reaction, Complement Fixation.
9) Mechanism & Tissue Injury, Inflammation, Acute-Chronic Phases.
10) Mechanisms of Tissue Injury: Immunologic Reactions, Ancyphylaxis, Antigen-Antibody Complexes, Serum Sickness, Delayed Hypersensitivity.
11) Mechanism of Immunity to Parasitic Disease and Fungal
12) Mechanism of Immunity to Bacterial Disease: Non-specific, Specific.
13) Mechanism of Immunity to Viral Diseases
14) Immune Defenses in Tumor Immunity

Sources

Course Notes / Textbooks: Joseph A Bellanti, Immunology III , WB Saunders Co. Philadelphia, 1985
References:

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Attendance 10 % 0
Quizzes 1 % 10
Midterms 1 % 30
Final 1 % 60
Total % 100
PERCENTAGE OF SEMESTER WORK % 40
PERCENTAGE OF FINAL WORK % 60
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 3 42
Study Hours Out of Class 14 6 84
Presentations / Seminar 1 3 3
Quizzes 1 3 3
Midterms 1 3 3
Final 1 3 3
Total Workload 138

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution
1) Adequate knowledge of subjects specific to mathematics (analysis, linear, algebra, differential equations, statistics), science (physics, chemistry, biology) and related engineering discipline, and the ability to use theoretical and applied knowledge in these fields in complex engineering problems.
2) Identify, formulate, and solve complex Biomedical Engineering problems; select and apply proper modeling and analysis methods for this purpose 1
3) Design complex Biomedical systems, processes, devices or products under realistic constraints and conditions, in such a way as to meet the desired result; apply modern design methods for this purpose. 1
4) Devise, select, and use modern techniques and tools needed for solving complex problems in Biomedical Engineering practice; employ information technologies effectively. 2
5) Design and conduct numerical or physical experiments, collect data, analyze and interpret results for investigating the complex problems specific to Biomedical Engineering. 4
6) Cooperate efficiently in intra-disciplinary and multi-disciplinary teams; and show self-reliance when working on Biomedical Engineering-related problems. 4
7) Ability to communicate effectively in Turkish, oral and written, to have gained the level of English language knowledge (European Language Portfolio B1 general level) to follow the innovations in the field of Biomedical Engineering; gain the ability to write and understand written reports effectively, to prepare design and production reports, to make effective presentations, to give and receive clear and understandable instructions. 4
8) Recognize the need for life-long learning; show ability to access information, to follow developments in science and technology, and to continuously educate oneself. 1
9) Having knowledge for the importance of acting in accordance with the ethical principles of biomedical engineering and the awareness of professional responsibility and ethical responsibility and the standards used in biomedical engineering applications 1
10) Learn about business life practices such as project management, risk management, and change management; develop an awareness of entrepreneurship, innovation, and sustainable development. 2
11) Acquire knowledge about the effects of practices of Biomedical Engineering on health, environment, security in universal and social scope, and the contemporary problems of Biomedical Engineering; is aware of the legal consequences of Mechatronics engineering solutions. 4