DENTAL MEDICINE
Bachelor TR-NQF-HE: Level 6 QF-EHEA: First Cycle EQF-LLL: Level 6

Course Introduction and Application Information

Course Code Course Name Semester Theoretical Practical Credit ECTS
BME2063 Biomaterials Spring 3 0 3 5
This catalog is for information purposes. Course status is determined by the relevant department at the beginning of semester.

Basic information

Language of instruction: English
Type of course: Non-Departmental Elective
Course Level: Bachelor’s Degree (First Cycle)
Mode of Delivery: Face to face
Course Coordinator : FIRAT MATUR
Course Lecturer(s): Dr. Öğr. Üyesi BURCU TUNÇ ÇAMLIBEL
Recommended Optional Program Components: None
Course Objectives: In this course, students will learn biomaterials, understand principles of general chemistry, learn how to use engineering skills to deal with the challenges in biomaterials and tissue engineering, learn types of biomaterials, the interactions between materials and body, production techniques and the future trends.

Learning Outcomes

The students who have succeeded in this course;
Bu dersin sonunda öğrenci şunları yapabilecektir:
1- Biyomalzemelerin ve biyouyumluluğun temel özelliklerini anlayabilecektir,
2- Farklı bağlanma türlerini ve bunların metal, seramik ve polimerler için malzeme alt birimlerinde nasıl organize edildiğini anlamak,
3- Her bir malzeme sınıfı için mekanik özelliklerin arkasındaki moleküler mekanizmaların yanı sıra biyomalzemeleri güçlendiren ve zayıflatan olayların arkasındaki ilkeleri anlayın,
4- Yüzey özellikleri, toksisite ve malzeme karakterizasyon tekniklerini anlamak,
5- İnsan vücudundaki metallerin, seramiklerin ve polimerlerin çevresel bozunmasının arkasındaki moleküler mekanizmaları anlamak.
6- Biyomalzeme çalışmasının neden biyomedikal mühendisinin eğitim geçmişinin önemli bir yönü olduğunu anlamak ve biyomalzeme bilimi ile ilgili araştırma yapabilmek ve çalışmalarını sunabilmek

Course Content

Basic concepts of biomaterials science, the structure of metals, ceramics, polymers and composite biomaterials, biocompatibility, corrosion and degradation of biomaterials, surface properties of biomaterials.

Weekly Detailed Course Contents

Week Subject Related Preparation
1) Biyomalzemeye giriş Biyomedikal uygulamalar için malzemeler Read the Syllabus. Read these sections in text and reference books
2) Chemical structure of biomaterials Read these sections in text and refernce books
3) Chemical structure of biomaterials, cont. Read these sections in text and refernce books
4) Physical properties of biomaterials Read these sections in text and refernce books
5) Mechanical properties of biomaterials Read these sections in text and refernce books
6) Biomaterial degradation Biomaterial processing Read these sections in text and refernce books
7) Surface properties of biomaterials Read these sections in text and refernce books
8) Protein interactions with biomaterials - Part 1 Read these sections in text and refernce books
9) Protein interactions with biomaterials - Part 2 Read these sections in text and refernce books
10) Cell interaction with biomaterials Read these sections in text and refernce books
11) Biomaterial implantation and acute inflammation. Wound healing and the presence of biomaterials. Read these sections in text and refernce books
12) Immune response to biomaterials. Biomaterials and thrombosis. Read these sections in text and refernce books
13) Infection, tumorigenesis and calcification of biomaterials Read these sections in text and refernce books
14) Term project presentations Reasearch and prepare presentations

Sources

Course Notes / Textbooks: • Biomaterials, The Intersection of Biology and Materials Science by Temenoff and Mikos, 2nd ed., Pearson, 2022.
• Biomaterials Science: An Introduction to Materials in Medicine, Rattner BD, Hoffman AS, Schoen FJ, and Lemons JE, 4th ed., Elsevier Academic Press, San Diego, CA, 2020.



References: • Biomaterials, an Introduction by Park and Lakes, Springer, Third ed., 2007.
• Biomaterials, Principles and Applications, Park JB, Bronzino JD, CRC Press 2003.

Evaluation System

Semester Requirements Number of Activities Level of Contribution
Presentation 1 % 0
Project 1 % 30
Midterms 1 % 30
Final 1 % 40
Total % 100
PERCENTAGE OF SEMESTER WORK % 30
PERCENTAGE OF FINAL WORK % 70
Total % 100

ECTS / Workload Table

Activities Number of Activities Duration (Hours) Workload
Course Hours 14 3 42
Study Hours Out of Class 14 3 42
Presentations / Seminar 1 8 8
Project 1 40 40
Midterms 1 3 3
Final 1 3 3
Total Workload 138

Contribution of Learning Outcomes to Programme Outcomes

No Effect 1 Lowest 2 Low 3 Average 4 High 5 Highest
           
Program Outcomes Level of Contribution